Results 51 to 60 of about 514,902 (292)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Journal of Medical Case Reports, 2021 Background Autoimmune hepatitis–primary sclerosing cholangitis overlap syndrome is a form of autoimmune hepatitis with cholestatic features and is characterized by negative anti-mitochondrial antibody and cholangiographic changes on magnetic resonance ...
Behzad Hatami +2 more
doaj +1 more source
Uninvestigated Dyspepsia and Heartburn Overlap Syndrome at Industrial Hub of Eastern Siberia
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2021 Aim. A study of the overlap syndrome of uninvestigated dyspepsia and heartburn at an industrial hub city of Eastern Siberia.Materials and methods. A total of 1,382 subjects (684 men and 698 women, mean age 40.6 years) were randomly selected and examined ...
V. V. Tsukanov +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
An Autoimmune Overlap Syndrome in Diseases of the Thyroid Gland — Terra Incognita of Thyroidology
Mìžnarodnij Endokrinologìčnij Žurnal, 2016 Quite frequent thyroid pathology is an autoimmune disease. However, along with common autoimmune thyroid diseases — Graves’ disease, autoimmune thyroiditis, in clinical practice there are autoimmune overlap syndromes, which are characterized by a ...
H.F. Hendeleka
doaj +1 more source
Asthma-COPD Overlap Syndrome : a review of current knowledge and future directions [PDF]
, 2017 Asthma and chronic obstructive pulmonary disease are common diseases both characterised by airflow obstruction. Over recent decades the prevailing belief was that asthma and COPD were distinct diseases that can be easily distinguished and require ...
Johnston, Sebastian Lennox +1 more
core
Robust Machine Learning-Based Correction on Automatic Segmentation of the Cerebellum and Brainstem. [PDF]
, 2016 Automated segmentation is a useful method for studying large brain structures such as the cerebellum and brainstem. However, automated segmentation may lead to inaccuracy and/or undesirable boundary.
Hagerman, Randi J +4 more
core +3 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Determination of The Relationship Between Severity of Obstructive Sleep Apnea And Chronic Obstructive Pulmonary Disease [PDF]
Journal of Cardio-Thoracic Medicine, 2017 Introduction: Chronic obstructive pulmonary disease (COPD) patients are at increased risk of sleep-disorders. The concomitant occurrence of COPD and obstructive sleep apnea hypopnea syndrome (OSAHS) is named overlap syndrome. This study aimed to evaluate
Vahid Dehestani +5 more
doaj +1 more source