Results 61 to 70 of about 2,301 (237)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Results and limitations of outpatient and overnight stay laminectomies for lumbar spinal stenosis [PDF]

Canadian Journal of Surgery, 2017
At our centre, laminectomies have been traditionally performed as inpatient surgery. A gradual change in practice occurred between 2010 and 2013 to try to do these procedures as outpatient or overnight stay surgery.We conducted a retrospective cohort study of consecutive patients having laminectomies over 2 18-month periods: before the change in ...
David, Yen, Abdu, Albargi
openaire   +2 more sources

The COVID‐19 pandemic‐induced behavioral restrictions and their impact on child and adolescent psychiatric units—Infection control or freedom

PCN Reports
Aim This study examines the impact of COVID‐19 pandemic‐induced behavioral restrictions on child psychiatric inpatients in Japan, particularly focusing on limitations placed on outings and overnight stays as infection‐control measures.
Masahide Usami, Yoshinori Sasaki, Mayuna Ichikawa, Miki Matsudo, Mutsumi Ohashi, Yui Higashino, Yusuke Kono, Haruna Matsudo, Yuki Nomura, Minjae Ma, Yuuki Sakoh, Maiko Odaka, Kotoe Itagaki, Keita Yamamoto, Momoka Takahashi, Yuta Yoshimura, Saori Inoue, Masahiro Ishida, Kumi Inazaki, Yuki Hakoshima, Yuki Mizumoto   +20 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

TOURISM SEASONALITY IN THE SPAS OF ROMANIA [PDF]

Geo Journal of Tourism and Geosites, 2018
The paper aims at presenting the seasonality as one of the most important elements that influences significantly the tourist activities. The research methododology deals with the statistical analyze of the basic indicators that define the seasonal flows –
Marius I. STUPARIU, Cezar MORAR
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Post-separation patterns of children's overnight stays with each parent: A detailed snapshot

, 2020
Despite widespread interest in patterns of parenting after separation over the past decade - especially in shared-time arrangements - few studies have explored the detail of post-separation parenting time schedules.
Smyth, Bruce, Son, Vu, Allen, Elizabeth (Liz), Rodgers, Bryan   +3 more
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source