Results 81 to 90 of about 192,860 (277)

Overnight Stock Returns and Time-varying Correlations [PDF]

open access: yes
Time-varying correlation of the stock market returns across countries in the context of international investments has been well researched in the literature in last few years.
Pandey, Ajay
core  

Physical inactivity and television-viewing time among Aboriginal adults with asthma: a cross-sectional analysis of the Aboriginal Peoples Survey

open access: yesHealth Promotion and Chronic Disease Prevention in Canada, 2015
The purpose of this analysis was to (1) determine the association between asthma and physical activity levels or sedentary time among Aboriginal adults, and (2) understand the influence of physical inactivity and sedentary time on health care use among ...
N. Doggett, S. Dogra
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Analyzing Seasonality and Forecasting the Number of Tourists’ Overnight Stays in Constanta Municipality [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2017
Constanta is perceived as the country’s largest port-city, but also as the most visited tourist cityon the Romanian Black Sea coast. For many generations, Constanta has been the place wheremany beautiful summer holidays memories are made, being ...
Aivaz Kamer Ainur   +2 more
doaj  

TOURISM MANAGEMENT EXPLAINED BY THE CORRELATION BETWEEN THE AVERAGE TOTAL INCOME PER PERSON AND THE NUMBER OF OVERNIGHT STAYS IN ACCOMMODATION UNITS [PDF]

open access: yesBusiness Excellence and Management
In Romania’s tourism industry, in the last decade, following the European trend, small dimensioned accommodation units have appeared, bearing the name of boutique guesthouses or boutique hotels, depending on their accommodation capacity.
Alina GHEORGHE
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Gradualism, Transparency and Improved Operational Framework: A Look at the Overnight Volatility Transmission [PDF]

open access: yes
This paper proposes a possible way of assessing the effect of interest rate dynamics on changes in the decision-making approach, communication strategy and operational framework of a Central bank.
Silvio Colarossi, Andrea Zaghini
core  

Liquidity Risk, Credit Risk and the Overnight Interest Rate Spread: A Stochastic Volatility Modelling Approach [PDF]

open access: yes
In this paper we model the volatility of the spread between the overnight interest rate and the central bank policy rate (the policy spread) for the euro area and the UK during the two main phases of the financial crisis that began in late 2007.
John Beirne   +2 more
core   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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