Results 81 to 90 of about 2,301 (237)

Overnight stay in Spanish emergency departments and mortality in older patients

open access: yesInternal and Emergency Medicine
Abstract OBJECTIVE: To assess whether older adults who spend a night in emergency departments (ED) awaiting admission are at increased risk of mortality. METHODS: This was a retrospective review of a multipurpose cohort that recruited all patients ≥75 years who visited ED and were admitted to hospital on April 1 to 7, 2019, at 52 EDs across ...
Òscar Miró   +27 more
openaire   +3 more sources

Analyzing the Concentration of Overnight Stays in Constanta City, over the Period 2010-2016 [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2017
In tourism literature, seasonality is approached as an evolution mode of the activity and, inmost cases, it is seen as a problem faced by tourist destinations/ units, but also by other economicand social agents connected to the tourism activity ...
Jugănaru Mariana   +2 more
doaj  

Structural survey of day and overnight recreation, 1982

open access: yes, 2007
Information on leisure behaviour of the Dutch population regarding short holidays and day trips. Description of all recreational day trips ( P0752c ) and short holidays ( P0752b ) made by respondent during the spring and summer of 1982 / destination ...
Centraal Bureau voor de Statistiek, CBS * Voorburg (primary investigator)
core   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

TOURISM MANAGEMENT EXPLAINED BY THE CORRELATION BETWEEN THE AVERAGE TOTAL INCOME PER PERSON AND THE NUMBER OF OVERNIGHT STAYS IN ACCOMMODATION UNITS [PDF]

open access: yesBusiness Excellence and Management
In Romania’s tourism industry, in the last decade, following the European trend, small dimensioned accommodation units have appeared, bearing the name of boutique guesthouses or boutique hotels, depending on their accommodation capacity.
Alina GHEORGHE
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Analysis of the number of overnight stays and the number of foreign tourists in the Republic of Macedonia in the period 2006-2015 [PDF]

open access: yes, 2017
This paper analyzes two aspects of foreign tourists traffic in the Republic of Macedonia. The first aspect deals with the number of foreign tourists’ overnight stays between 2006 and 2015, while the second aspect analyzes the number of tourists who ...
Majhosev, Darko, Koteski, Cane
core  

Effects of price model copycats in the ski industry

open access: yes, 2021
This article investigates the impact of the introduction of a greatly reduced seasonal ski pass for overnight stays in winter destinations. The analysis covers 59 winter sports destinations in Switzerland for the winter seasons 2012/2013 to 2017/2018, of
Falk, Martin, Scaglione, Miriam
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

CULTIVATING HOSPITALITY AGRITOURISM: Exploring Farm-Stays in Rural Oregon [PDF]

open access: yes, 2019
92 pagesOregon's Statewide Planning Program, first established in 1973, protects farmland from urban development through Urban Growth Boundaries (UGB) and Exclusive Farm Use zoning (EFU).
Shinners, Dana
core  

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