Results 41 to 50 of about 768,505 (310)

Genetic Testing Oversight [PDF]

Science, 2006
![Figure][1] A major impact of sequencing the human genome has been the ability to detect disease and the risk of disease through genetic testing. Today, there are genetic tests for more than 1000 diseases, and that number is increasing rapidly. Given the potential powerful health consequences of genetic test results, shouldn't someone be in charge ...
openaire   +2 more sources

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego, Kellee Parker, William C. Thomsen, James B. Ford, Mallorie B. Heneghan, David Spencer Mangum, Jennifer L. McNeer, Luke D. Maese, Claire E. F. Miller, Richard Lemons, Taumoha Ghosh   +10 more
wiley   +1 more source

How perceptions of raw data collection affect intelligence accountability: the Danish intelligence field

Frontiers in Political Science
The collection of raw data has become a central aspect of intelligence accountability. This study investigates the relationship between perceptions of raw data collection and intelligence accountability virtues within a coherent framework, aiming to ...
Melanie Sofia Hartvigsen
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Current practice and perspectives in CRO oversight based on a survey performed among members of the German Association of Research-Based Pharmaceutical Companies (vfa)

GMS German Medical Science, 2017
In recent years, the number and scope of outsourced activities in the pharmaceutical industry have increased heavily. In addition, also the type of outsourcing has changed significantly in that time.
Hennig, Michael, Hundt, Ferdinand, Busta, Susanne, Mikus, Stefan, Sanden, Per-Holger, Sörgel, Andrea, Ruppert, Thorsten   +6 more
doaj   +1 more source

Charity Oversight: An Alternative Approach [PDF]

, 2006
In this paper, a former director of the Internal Revenue Services Exempt Organization Division argues that the IRS is structurally ill suited for the task of providing vigorous oversight of the nations growing number of nonprofit organizations.
Marcus S. Owens
core  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Shariah governance effects on cash holdings under sustainability commitments: Indonesian Islamic banks [PDF]

Banks and Bank Systems
Type of the article: Research Article AbstractThis study investigates the link between sustainability commitment and cash holdings and assesses the relationship between board meetings (BM), industry knowledge (IK), and Shariah Supervisory Boards (SSBs ...
Tettet Fitrijanti, Prasojo, Nunuy Nur Afiah, Sofyan Hadinata   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Oversight, Accountability, or Influence? Understanding the Use of Monetary Dialogues in the European Parliament

Politics and Governance
The Monetary Dialogue (MD) between the European Central Bank (ECB) and the European Parliament (EP) has received ample research that has offered an insightful discussion on the effectiveness of the dialogue as a forum for ECB accountability.
Amie Kreppel, Corinne Tomasi
doaj   +1 more source