Results 51 to 60 of about 768,505 (310)
Comparing Regulatory Oversight Bodies Across the Atlantic: The Office of Information and Regulatory Affairs in the US and the Impact Assessment Board in the EU [PDF]
, 2011 ‘Quis custodiet ipsos custodes?’ asked the Roman poet Juvenal – ‘who will watch the watchers, who will guard the guardians?’ As legislative and regulatory processes around the globe progressively put greater emphasis on impact assessment and ...
Wiener, Jonathan B., Alemanno, Alberto
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
INTELLIGENCE ACTIVITY IN LATIN AMERICA: CHARACTERISTICS, STRENGTHS, WEAKNESSES, AND FUTURE PROSPECTS
Política y Estrategia, 2017 Intelligence activity in Latin America has had an interesting evolution in recent years. Emerged or developed in most countries of the region during the Cold War, their characteristics were influenced by the existing concepts of defense and security in ...
JOSÉ MANUEL UGARTE
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Cogent Social SciencesThis paper explores the persistent non-implementation of recommendations by South Africa’s Public Service Commission (PSC), constitutionally mandated to promote accountability, ethical governance, and efficiency.
Lesedi Senamele Matlala
doaj +1 more source
The creation of a contagious H5N1 influenza virus: implications for the education of life scientists [PDF]
The Ukrainian Biochemical Journal, 2014 The paper contends that the ongoing controversy surrounding the creation of a contagious H5N1 influenza virus has already exposed the severe limitations of the possibility of preventing the hostile misuse of the life sciences by dint of oversight of ...
T. Novossiolova, M. Minehata, M. Dando
doaj +1 more source
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Clinical case of co-infection: Dengue fever and respiratory mycoplasmosis in a child
Respiratory Medicine Case ReportsAccording to WHO, dengue fever (DF) is currently endemic to more than 100 countries in various regions of Africa, America, and Asia; outbreaks have been reported in Europe.
D.V. Preobrazhenskaia +2 more
doaj +1 more source