Results 41 to 50 of about 1,483,118 (292)

Sondrestrom overview

open access: yesGeophysical Research Letters, 1984
This overview of the Sondrestrom radar provides background material to help understand the early scientific results discussed in the following series of papers. It describes the geophysical region probed by the radar, the data acquisition procedure, and the extensive set of physical parameters derived.
Wickwar, Vincent B.   +5 more
openaire   +3 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Shining light on knee osteoarthritis: an overview of vitamin D supplementation studies

open access: yesFrontiers in Medicine
BackgroundThe impact of knee osteoarthritis on individuals’ daily functioning is significant. In recent years, Vitamin D supplements cure osteoarthritis has garnered attention from medical professionals and patients due to its simplicity and portability.
Di Zhang   +10 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Advances and Future Prospects in Building Extraction From High-Resolution Remote Sensing Images

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Automatic building extraction from high resolution remains challenging for wide applications. Previous studies have reviewed building extraction methods, but rapid advances in deep learning (DL) highlight the need for an updated review focused on high ...
Dongjie Yang   +5 more
doaj   +1 more source

An Overview on Solid Waste Generation and Management: Current Status in Chile [PDF]

open access: gold, 2021
R. Cayumil   +5 more
openalex   +1 more source

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