Results 41 to 50 of about 6,251,767 (305)

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

Advances in Formation Evaluation and Well Logging Technology: Overview of the SPWLA 63rd Annual Logging Symposium

open access: yesCejing jishu, 2023
Annual logging symposium of Society of Petrophysicists and Well Log Analysts (SPWLA) is an important platform for international advanced well logging technology communication.
WANG Xiaoning   +5 more
doaj   +1 more source

Overview

open access: yesZootaxa, 2011
  At about this time last year, one of us (MRC) edited a manuscript submitted by systematic ichthyologists Randall D. Mooi and Anthony C. Gill to Zootaxa entitled “Phylogenies without synapomorphies—a crisis in fish systemat­ics: time to show some character” (Mooi & Gill, 2010; hereafter M&G).
De Carvalho, Marcelo R.   +1 more
openaire   +2 more sources

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

An Overview of Systematic Reviews of Chinese Herbal Medicine for Parkinson's Disease

open access: yesFrontiers in Pharmacology, 2019
Parkinson's disease (PD) is a high prevalence neurodegenerative disorder without a disease-modifying therapy. Up to now, a number of systematic reviews have been conducted to evaluate efficacy and safety of Chinese herbal Medicine (CHM) for PD patients ...
Xin-Chun Jin   +7 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Development of microwave chemistry through a co-operation between a university and an equipment manufacturer

open access: yesGreen Processing and Synthesis, 2012
This mini-overview focuses on selected important details of reaction engineering in microwave chemistry and discusses the co-operation between the university working group “Alternative Energies” in Jena and the microwave plant MLS GmbH (Leutkirch/Germany)
Ondruschka Bernd, Lautenschläger Werner
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Overview of the Issue [PDF]

open access: yesJournal of Pension Economics and Finance, 2002
Since the inception of the Journal, it has been published in conjunction with the International Network of Pension Regulators and Supervisors (INPRS), a network setup and administered by the OECD. Because of the importance of pension supervision, it has become clear that a network such as the INPRS is not enough and as a result a new international ...
Mike Orszag   +3 more
openaire   +3 more sources

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