OvHV-2 Glycoprotein B Delivered by a Recombinant BoHV-4 Is Immunogenic and Induces Partial Protection against Sheep-Associated Malignant Catarrhal Fever in a Rabbit Model [PDF]
Vaccines, 2021 An efficacious vaccine for sheep-associated malignant catarrhal fever (SA-MCF) is important for the livestock industry. Research towards SA-MCF vaccine development is hindered by the absence of culture systems to propagate the causative agent, ovine ...
Smriti Shringi +2 more
exaly +4 more sources
Evaluation of glycoprotein Ov8 as a potential antigen for an OvHV-2-specific diagnostic assay [PDF]
PLoS ONE, 2018 Gammaherpesviruses in the genus Macavirus establish clinically unapparent persistent infections in reservoir species. Transmission of some of these viruses, including alcelaphine herpesvirus 1 (AlHV-1) and ovine herpesvirus 2 (OvHV-2), to clinically ...
Cristina W Cunha +2 more
exaly +3 more sources
Malignant Catarrhal Fever in Sardinia (Italy): A Case Report [PDF]
Veterinary Sciences, 2022 Using a multidisciplinary approach, this report describes a clinical case of malignant catarrhal fever (MCF) occurring in a calf, which shared the pasture with sheep on a farm located in the island of Sardinia (Italy).
Elisabetta Coradduzza +2 more
exaly +4 more sources
First identification and characterization of ovine gammaherpesvirus type 2 in horses and artiodactyla from an outbreak of malignant catarrhal fever in Mexico. [PDF]
PLoS ONE, 2023 Ovine gammaherpesvirus 2 (OvHV-2), a member of the genus Macavirus, causes sheep-associated malignant catarrhal fever (SA-MCF), a fatal lymphoproliferative disease affecting a wide variety of ungulates in addition to horses.
Tania Lucia Madrigal-Valencia +8 more
doaj +4 more sources
A Vaccine Targeting Ovine Herpesvirus 2 Glycoprotein B Protects against Sheep-Associated Malignant Catarrhal Fever [PDF]
Vaccines, 2022 Malignant catarrhal fever (MCF) is a complex and often fatal disease of ungulates. Effective vaccines are needed to avoid MCF outbreaks and mitigate losses.
Cristina W. Cunha +7 more
doaj +2 more sources
Detection and characterisation of sheep-associated malignant catarrhal fever infection from ruminants by using tegument and gB gene sequences of OvHV-2 [PDF]
Onderstepoort Journal of Veterinary Research, 2020 In this study, positive blood and organ samples were obtained from different mixed herds of sheep and cattle against ovine herpesvirus 2 (OvHV-2) infection.
Tuba Ç. Oğuzoğlu +4 more
doaj +2 more sources
The Cytoplasmic Tail of Ovine Herpesvirus 2 Glycoprotein B Affects Cell Surface Expression and Is Required for Membrane Fusion [PDF]
VirusesOvine herpesvirus 2 (OvHV-2) causes the fatal veterinary disease malignant catarrhal fever (MCF). Fusion is an essential step in the host cell entry of enveloped viruses and is an important target for vaccine development.
Colleen M. Lynch +6 more
doaj +2 more sources
Ovine Herpesvirus 2 Glycoprotein B Complementation Restores Infectivity to a Bovine Herpesvirus 4 gB-Null Mutant [PDF]
PathogensOvine herpesvirus 2 (OvHV-2) and bovine herpesvirus 4 (BoHV-4) are gamma herpesviruses that belong to the genera Macavirus and Rhadinovirus, respectively.
Daniela D. Moré +6 more
doaj +2 more sources
Molecular prevalence and risk factors of ovine herpesvirus-2–associated malignant catarrhal fever in cattle from Riau Province, Indonesia: A cross-sectional nested polymerase chain reaction study [PDF]
Veterinary WorldBackground and Aim: Malignant catarrhal fever (MCF) is a highly fatal disease caused by ovine herpesvirus-2 (OvHV-2), with sheep acting as asymptomatic reservoir hosts.
Annisa Yohanes +5 more
doaj +2 more sources
First Molecular Evidence and Genetic Characterization of Ovine Herpesvirus 2 in Multiple Animal Species in India [PDF]
Frontiers in Veterinary Science, 2021 Ovine herpesvirus 2 (OvHV-2) is the causative agent of sheep-associated malignant catarrhal fever (SA-MCF), a highly fatal disease syndrome that predominantly affects susceptible hosts of the order Artiodactyla.
Naveen Kumar +7 more
doaj +2 more sources