Glycoprotein B Antibodies Completely Neutralize EBV Infection of B Cells [PDF]
Frontiers in Immunology, 2022 The Epstein–Barr virus (EBV) is the first reported oncogenic herpesvirus that establishes persistent infection in B lymphocytes in 95% of adults worldwide.
Junping Hong +10 more
doaj +4 more sources
The prefusion structure of herpes simplex virus glycoprotein B. [PDF]
Sci Adv, 2020 Elusive, pharmacologically relevant conformation of the herpesvirus fusion protein is revealed by a multi-methodological approach.
Vollmer B +11 more
europepmc +11 more sources
Distribution of CMV envelope glycoprotein B, H and N genotypes in infants with congenital cytomegalovirus symptomatic infection [PDF]
Frontiers in Pediatrics, 2023 BackgroundCytomegalovirus (CMV) is the leading cause of congenital infections worldwide and contributes to long-term sequelae in neonates and children. CMV envelope glycoproteins play a vital role in virus entry and cell fusion.
Niuniu Dong +8 more
doaj +2 more sources
Crystal Structure of the Human Cytomegalovirus Glycoprotein B. [PDF]
PLoS Pathogens, 2015 Human cytomegalovirus (HCMV), a dsDNA, enveloped virus, is a ubiquitous pathogen that establishes lifelong latent infections and caused disease in persons with compromised immune systems, e.g., organ transplant recipients or AIDS patients. HCMV is also a
Heidi G Burke, Ekaterina E Heldwein
doaj +4 more sources
Characterization of Murine Gammaherpesvirus 68 Glycoprotein B [PDF]
Journal of Virology, 2004 ABSTRACT Murine gammaherpesvirus 68 (MHV-68) glycoprotein B (gB) was identified in purified virions by immunoblotting, immunoprecipitation, and immunoelectron microscopy. It was synthesized as a 120-kDa precursor in infected cells and cleaved into 65-kDa and 55-kDa disulfide-linked subunits close to the time of virion release.
Lopes, Filipa B. +3 more
openaire +7 more sources
Structure and Antigenicity of Kaposi's Sarcoma‐Associated Herpesvirus Glycoprotein B [PDF]
Advanced ScienceKaposi's sarcoma‐associated herpesvirus (KSHV), a member of the human γ‐herpesviruses family, exhibits extensive cellular tropism and is associated with Kaposi's sarcoma and various B‐cell malignancies.
Xin‐Yan Fang +8 more
doaj +2 more sources
Correction: Crystal Structure of the Human Cytomegalovirus Glycoprotein B. [PDF]
PLoS Pathogens, 2015 The Funding Statement is missing funding information from the NIH. Please see the full Funding Statement here. This study was funded by the Burroughs Wellcome Fund Award for Investigators in Pathogenesis (EEH) and the NIH T32-{"type":"entrez-nucleotide","attrs":{"text":"AI007422","term_id":"3216932","term_text":"AI007422"}}AI007422 (HGB).
Heidi G Burke, Ekaterina E Heldwein
doaj +3 more sources
Growth defect of domain III glycoprotein B mutants of human cytomegalovirus reverted by compensatory mutations co-localizing in post-fusion conformation [PDF]
mBioCell entry is a crucial step for a virus to infect a host cell. Human cytomegalovirus utilizes glycoprotein B (gB) to fuse the viral and host cell membranes upon receptor binding of gH/gL-containing complexes.
Madlen Mollik +8 more
doaj +2 more sources
The Brain, Amphotericin B, and P-Glycoprotein [PDF]
Antimicrobial Agents and Chemotherapy, 2015 We read with interest the paper by Wu et al. ([1][1]) purporting to show that blockade of P-glycoprotein with verapamil or itraconazole increased brain concentrations of amphotericin B (AMB). Because virtually all P-glycoprotein blockers also block other transporters, we chose to compare P-
David A, Stevens +3 more
openaire +2 more sources
BMC Immunology, 2021 Background Currently, research on the quantitative distribution of ABO antigens in different organs and tissues remains limited. We aimed to examine the individual characteristics of blood group glycoprotein A and B antigen expression in human kidneys ...
Xianding Wang +10 more
doaj +1 more source