Results 31 to 40 of about 582,559 (301)

Characterization of antibody-mediated neutralization directed against the hypervariable region 1 of hepatitis C virus E2 glycoprotein [PDF]

, 2010
The hypervariable region 1 (HVR1) comprising the first 27 aa of E2 glycoprotein is a target for neutralizing antibodies against hepatitis C virus (HCV), but the mechanisms of this neutralization in the cell-culture-infectious genotype 2a strain JFH1 ...
Dubuisson, J., J. Dubuisson, A. H. Patel, G. Vieyres, Patel, A.H., Vieyres, G.   +5 more
core   +1 more source

Screening of Phenanthroquinolizidine Alkaloid Derivatives for Inducing Cell Death of L1210 Leukemia Cells with Negative and Positive P-glycoprotein Expression

Molecules, 2019
We describe the screening of a set of cryptopleurine derivatives, namely thienoquinolizidine derivatives and (epi-)benzo analogs with bioactive phenanthroquinolizidine alkaloids that induce cytotoxic effects in the mouse lymphocytic leukemia cell line ...
Jana Kubíčková, Katarína Elefantová, Lucia Pavlikova, Martin Cagala, Mário Šereš, Peter Šafář, Štefan Marchalín, Kamila Ďurišová, Viera Boháčová, Zdena Sulova, Boris Lakatoš, Albert Breier, Petra Olejníková   +12 more
doaj   +1 more source

Synthesis of antagonists of Myelin-associated glycoprotein (MAG) for conformational and SAR studies [PDF]

, 2004
Damage to the central nervous system (CNS) of higher vertebrates, including humans, often results in devastating and persistent functional deficits.
Gao, Gan-Pan
core   +1 more source

A fifth human cytomegalovirus glycoprotein B genotype

Research in Virology, 1998
Genetic variation in glycoprotein B (gB) may play a role in human cytomegalovirus (HCMV) pathogenesis. Using restriction endonuclease digestion and DNA sequencing, a unique gB genotype was identified in eight HCMV strains isolated from five patients with the acquired immune deficiency syndrome.
D H, Shepp, M E, Match, S M, Lipson, R G, Pergolizzi   +3 more
openaire   +2 more sources

Prognosis of Human Cytomegalovirus in Cancer Patients Undergoing Chemotherapeutic Treatment in Egypt and an Emergent Prevalence of Glycoprotein B-5

, 2022
The human cytomegalovirus (HCMV) is a global opportunistic β-herpes virus causing severe diseases in immune-compromised patients, such as malignant tumor patients, especially those undergoing chemotherapeutic treatment.
Sarah M. Abdelhamid, Rania Abozahra, Israa S. Shamsia, Kholoud Baraka, Ayman Abou Shmeila   +4 more
core   +1 more source

Distribution of B-cell epitopes on the pseudorabies virus glycoprotein B

Journal of General Virology, 1999
In order to map antigenically important regions of glycoprotein B (gB) of pseudorabies virus (PrV), a panel of recombinant fragments of gB expressed in E. coli and truncated fragments of gB generated by cleavage of purified native gB with trypsin and cyanogen bromide was analysed by using 26 monoclonal antibodies directed against gB.
Mikhail M. Zaripov, Oleg S. Morenkov, Nadja Fodor, Attila Braun, Vadim V. Schmatchenko, Istvan Fodor   +5 more
openaire   +3 more sources

Chelerythrine inhibits HSV-1 infection by suppressing virus binding to the cells

Pharmacological Research - Modern Chinese Medicine, 2023
Objective: Herpes simplex virus type 1 (HSV-1) is a worldwide pathogen and mainly puts immunocompromised patients at higher risk of various complications.
Ziwei Hu, Chaowei Zhang, Jianfeng Zhong, Hao Hu, Chenyang Li, Yunshi Zhao, Lu Wang, Liang Ye, Cong Yan, Mingzhong Wang, Qinchang Zhu, Bo Wen, Longxia He, Muhammad Shahid Riaz Rajoka, Xun Song, Zhendan He   +15 more
doaj   +1 more source

Cytomegalovirus Glycoprotein B Groups Associated with Retinitis in AIDS [PDF]

Journal of Infectious Diseases, 1996
To determine if cytomegalovirus (CMV) retinitis occurs more frequently in patients infected with certain strains CMV isolates from the blood of 44 patients with advanced human immunodeficiency virus disease were grouped by the DNA sequence or the restriction endonuclease digest pattern of a portion of the glycoprotein B (gB) gene.
D H, Shepp, M E, Match, A B, Ashraf, S M, Lipson, C, Millan, R, Pergolizzi   +5 more
openaire   +2 more sources

Functional properties of the spike glycoprotein of the emerging SARS-CoV-2 variant B.1.1.529

Cell Reports, 2022
Summary: The recently emerged B.1.1.529 (Omicron) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant has a highly divergent spike (S) glycoprotein.
Qian Wang, Saumya Anang, Sho Iketani, Yicheng Guo, Lihong Liu, Phinikoula S. Katsamba, Lawrence Shapiro, David D. Ho, Joseph G. Sodroski   +8 more
doaj   +1 more source

Spatiotemporal Expression of Pregnancy-Specific Glycoprotein Gene rnCGMl in Rat Placenta [PDF]

, 1993
As a basis towards a better understanding of the role of the pregnancy-specific glycoprotein (PSG) family in the maintenance of pregnancy, detailed investigations are described on the expression of a recently identified rat PSG gene (rnCGM1) at the mRNA ...
Wolfgang Zimmermann, Zimmermann, Wolfgang, Sabine Rebstock, Weiss, Martina, Martina Weiss, Lucas, Kurt, Kurt Lucas, John Thompson, Rebstock, Sabine, Thompson, John A.   +9 more
core   +1 more source