Results 11 to 20 of about 10,999 (207)

Integration of production and financial models to analyse the financial impact of livestock diseases: a case study of Schmallenberg virus disease on British and French dairy farms [PDF]

Veterinary Record Open, Volume 2, Issue 1, January 2015., 2015
AIMS AND OBJECTIVES: The aim of the study was to investigate and compare the financial impact of Schmallenberg disease for different dairy production types in the United Kingdom and France.
Alarcon, P, Hasler, B, Raboisson, D, Rushton, J, Waret-Szkuta, A   +4 more
core   +3 more sources

The Seizure-Associated Genes Across Species (SAGAS) database offers insights into epilepsy genes, pathways and treatments. [PDF]

Epilepsia, 2022
Abstract Objective Decades of genetic studies on people with many different epilepsies, and on many nonhuman species, using many different technologies, have generated a huge body of literature about the genes associated with seizures/epilepsy. Collating these data can help uncover epilepsy genes, pathways, and treatments that would otherwise be ...
Gracie L, Rostami-Hochaghan D, Taweel B, Mirza N, SAGAS Scientists' Collaborative.   +4 more
europepmc   +2 more sources

Statins as antiepileptogenic drugs: Analyzing the evidence and identifying the most promising statin. [PDF]

Epilepsia, 2022
Abstract Many brain insults and injuries are “epileptogenic”: they increase the risk of developing epilepsy. It is desirable to identify treatments that are “antiepileptogenic”: treatments that prevent the development of epilepsy, if administered after the occurrence of an epileptogenic insult. Current antiepileptic drugs are not antiepileptogenic, but
Hufthy Y, Bharadwaj M, Gupta S, Hussain D, Joseph PJS, Khan A, King J, Lahorgue P, Jayawardena O, Rostami-Hochaghan D, Smith C, Marson A, Mirza N.   +12 more
europepmc   +2 more sources

Unmasking the tumourigenic role of SIN1/MAPKAP1 in the mTOR complex 2. [PDF]

Clin Transl Med, 2023
SIN1 is a cornerstone subunit of mTORC2, stabilizing the complex and regulating its substrate specificity. SIN1 upregulation and overexpression are associated with many types of cancer and drive tumourigenesis. SIN1 is connected with other signaling pathways disrupted in cancer: Hippo, WNT, Notch, RAS and MAPK.
Ezine E, Lebbe C, Dumaz N.
europepmc   +2 more sources

Assessment of information as regards the toxicity of T-2 and HT-2 toxin for ruminants. [PDF]

EFSA J, 2022
Abstract In 2011, the EFSA Panel on Contaminants in the Food Chain (CONTAM) adopted a Scientific Opinion on the risks for animal health related to the presence of T‐2 (T2) and HT‐2 (HT2) toxin in food and feed. No observed adverse effect levels (NOAELs) and lowest observed adverse effect levels (LOAELs) were derived for different animal species.
EFSA Panel on Contaminants in the Food Chain (CONTAM), Schrenk D, Bignami M, Bodin L, Chipman JK, Del Mazo J, Grasl-Kraupp B, Hogstrand C, Leblanc JC, Nielsen E, Ntzani E, Petersen A, Sand S, Schwerdtle T, Vleminckx C, Wallace H, Daenicke S, Nebbia CS, Oswald IP, Rovesti E, Steinkellner H, Hoogenboom LR.   +21 more
europepmc   +2 more sources

The Inflation Reduction Act: A boon for the generic and biosimilar industry. [PDF]

J Clin Pharm Ther, 2022
The Inflation Reduction Act gives a significant boost to generics and biosimilars!Soon lowered out‐of‐pocket costBiosimilars promoted and adopted Abstract What is Known and Objective After more than a year of negotiation, a $740 billion climate and health care bill known as The Inflation Reduction Act (IRA) became law on 16 August 2022.
Niazi SK.
europepmc   +2 more sources

Analysis of Perception Variance in Regret Choice Modeling Based on GPS Data Considering Building Environment Effects

Journal of Advanced Transportation, Volume 2022, Issue 1, 2022., 2022
The purpose of this paper is to deal with the perception variance problem in regret model by scaling perception variance and relaxing the distribution assumption of the random error term, which are corresponding to the attribute and alternative differences, respectively.
Qiong Chen, Hong Zhang, Yuchen Song, Donghao Huang, Dawei Li, Haining Wang, Wen Liu   +6 more
wiley   +1 more source

Estimating the Potential Modal Split of Any Future Mode Using Revealed Preference Data

Journal of Advanced Transportation, Volume 2022, Issue 1, 2022., 2022
Mode choice behaviour is often modelled by discrete choice models, in which the utility of each mode is characterized by mode‐specific parameters reflecting how strongly the utility of that mode depends on attributes such as travel speed and cost, and a mode‐specific constant value.
Gijsbert Koen de Clercq, Arjan van Binsbergen, Bart van Arem, Maaike Snelder, Arkatkar Shriniwas   +4 more
wiley   +1 more source

Multilevel time series modelling of mobility trends in the Netherlands for small domains

Journal of the Royal Statistical Society: Series A (Statistics in Society), Volume 184, Issue 3, Page 985-1007, July 2021., 2021
Abstract The purpose of the Dutch Travel Survey is to produce reliable estimates on mobility of the Dutch population. In this paper mobility trends are estimated at several aggregation levels, using multilevel time series models. The models account for discontinuities induced by two survey redesigns and outliers due to less reliable outcomes in one ...
Harm Jan Boonstra, Jan van den Brakel, Sumonkanti Das   +2 more
wiley   +1 more source

Effect of Age and Breed on Carcass and Meat Quality Characteristics of Beni‐Guil and Ouled‐Djellal Sheep Breeds

The Scientific World Journal, Volume 2021, Issue 1, 2021., 2021
Two hundred eight sheep, belonging to two main breeds of eastern Morocco, “Beni‐Guil” and “Ouled‐Djellal,” were investigated for carcass traits and meat quality. The objective of this study is to determine the effects of breed and age at slaughter on carcass traits and meat quality. The animals were slaughtered at three age classes: milk teeth, animals
Kamal Belhaj, Farid Mansouri, Aziz Tikent, Yassin Taaifi, Mohamed Boukharta, Hana Caid Serghini, Ahmed Elamrani, Piotr Minkiewicz   +7 more
wiley   +1 more source