Results 101 to 110 of about 33,909 (197)

Design, Synthesis, and Evaluation of Bis‐Chalcones and Bis‐Flavones as Selective COX‐2 Inhibitors

Chemical Biology &Drug Design, Volume 107, Issue 3, March 2026.
Novel bis‐chalcones were successfully synthesized and demonstrated COX‐2 selective inhibition and the ability to inhibit PGE2 production in whole human blood. Notably, a monomeric chalcone with a similar substitution pattern exhibited even greater activity, providing valuable insights to guide the future design and optimization of flavonoid‐based COX‐2
Rui Pereira, Marisa Freitas, Alberto N. Araújo, Vera L. M. Silva, Eduarda Fernandes   +4 more
wiley   +1 more source

A Systematic Review of the Cost‐Effectiveness of Interventions for Chronic Wounds

International Wound Journal, Volume 23, Issue 3, March 2026.
ABSTRACT Chronic wounds present a significant challenge to society and have a negative impact on the quality of life and daily activities of patients. This review aimed to identify the cost‐effectiveness of the currently used care alternatives for the treatment of chronic wounds. This study serves to identify cost‐effectiveness boundaries and provide a
Petra Marešová, Kristina Randlová, Lukáš Režný, Jan Hruška, Barbara Wolff‐Winiski, Damien Dupin, Kamil Kuča   +6 more
wiley   +1 more source

Elemental Composition Analysis of Sheep Tears Using Particle‐Induced X‐Ray Emission

Veterinary Ophthalmology, Volume 29, Issue 2, March 2026.
ABSTRACT Objective To identify the elemental composition of ovine tears using particle‐induced X‐ray emission (PIXE). Animals Studied Ten physically healthy female sheep. Procedures Tear samples were collected using Schirmer tear test strips. Tear samples were collected once daily over five consecutive days to assess reproducibility. Elemental analysis
Alon Zahavi, Oren Pe'er, Noa Cohen Sinai, Yoav Vardizer, Lionel Sebbag, Ron Ofri, Olga Girshevitz, Nitza Goldenberg‐Cohen   +7 more
wiley   +1 more source

Visualization of Ex Vivo Porcine Corneal Endothelial Cells Using Smartphone‐Assisted Specular Reflection With Slit‐Lamp Biomicroscopy

Veterinary Ophthalmology, Volume 29, Issue 2, March 2026.
ABSTRACT Objective To visualize corneal endothelial cells in enucleated porcine eyes using slit‐lamp imaging with a mobile smartphone (SLiM), determine optimal illumination conditions, and explore agreement between SLiM and vital dye stained imaging. Animals Studied Twelve enucleated porcine eyes.
Yujin Kim, Seonmi Kang, Kangmoon Seo
wiley   +1 more source

Antenatal betamethasone impairs markers of cardiac development and function in near‐term lambs

Experimental Physiology, Volume 111, Issue 3, Page 988-1007, 1 March 2026.
Abstract figure Summary of key molecular differences in the left ventricle of near‐term lambs exposed to antenatal betamethasone, compared to saline. Pregnant ewes received two doses of either saline (Saline) or betamethasone (Betamethasone, intramuscular, 11.4 mg) given 24 h apart, before delivery at 140 days of gestation (dG, term = 150 dG).
Reza Amanollahi, Ashley S. Meakin, Stacey L. Holman, Vicki L. Clifton, Kent L. Thornburg, Michael D. Wiese, Kathryn L. Gatford, Mitchell C. Lock, Janna L. Morrison   +8 more
wiley   +1 more source

Comparative analysis of ovine and human aortic valve tissue for bioprosthetic valve development using relaxation tests and numerical simulation. [PDF]

Sci Rep
Masoumi SF, Rassoli A, Changizi S, Ravaghi S, Fatouraee N.   +4 more
europepmc   +1 more source

Ovine bone graft enhances osteogenic commitment in human osteoblasts via selective suppression of miR-6797-5p: In silico and in vitro study. [PDF]

J Oral Biol Craniofac Res
Sethi A, Shah KK, Ganapathy D, Abullais SS, Almuaddi A, Sekaran S.   +5 more
europepmc   +1 more source

Identification of single nucleotide polymorphisms in sheep Mx genes: A premature stop codon abolishes Mx2 protein expression but did not affect fertility and early animal development. [PDF]

PLoS One
Lee CE, Moradi N, Hine B, Andronicos NM, McNally J, Liu JW, Strive T, Smith I, Hunt PW, Frese M.   +9 more
europepmc   +1 more source

Detecting the body's reproductive hormonal brake against tissue overgrowth: Micrin/SgII-70. [PDF]

PLoS One
Hart JE, Davies KG, Mundy CR, Hart AC, Howlett DR, Newton RP.   +5 more
europepmc   +1 more source

Ovine models of intervertebral disc degeneration. [PDF]

Ann Transl Med
Bonilla AF, Seim HB, Gadomski B, Patel VV, Easley JT.   +4 more
europepmc   +1 more source