Results 101 to 110 of about 36,935 (226)

Media Supplementation With Gamma‐Oryzanol Improves the Outcome of Ovine Oocyte Maturation In Vitro

Veterinary Medicine and Science
Background The process of maturing ovine oocyte in vitro has not yet been raised with acceptable results. Objective This study was designed to evaluate the γ‐oryzanol effect as a supplement of maturation media on the development of ovine oocytes to ...
Saeed Musapoor, Najmeh Davoodian, Ali Kadivar, Ebrahim Ahmadi, Hassan Nazari   +4 more
doaj   +1 more source

Strategic Design of Soft Actuators in Translational Medical Robotics for Human‐Centered Healthcare

Advanced Robotics Research, Volume 2, Issue 5, October 2026.
Soft robotics enables biocompatible, compliant medical devices, but clinical translation requires design‐driven engineering beyond materials. This perspective reviews implantable, surgical, and wearable systems by actuation mechanism, highlighting how optimized architectures and integration improve mechanical interfacing, adaptability, and durability ...
Ho Jun Jin, Jimin Kim, Inho Kim, Bong Hoon Kim   +3 more
wiley   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, Volume 13, Issue 56, 9 October 2026.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, Volume 13, Issue 56, 9 October 2026.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source

Genome‐Wide Characterization of Heterozygosity‐Rich Regions in Kazakh Native Sheep Breeds

Animal Genetics, Volume 57, Issue 5, October 2026.
ABSTRACT Heterozygosity‐rich regions (HRR) are genomic segments characterized by high heterozygosity that may arise from admixture, introgression, or balancing selection and may harbor loci associated with adaptation and fitness‐related traits. This study aimed to characterize HRR patterns in five Kazakh sheep breeds using a publicly available ...
Sholpan Bakhtybekkyzy, Zarina Orazymbetova, Aizhan Mussayeva, Aidana Bekitayeva, Ajoy Mandal, Hasan Baneh   +5 more
wiley   +1 more source

Oocyte–cumulus cell interaction: a key factor in early embryo development

Biological Reviews, Volume 101, Issue 5, Page 2265-2278, October 2026.
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido, Marc Yeste, Yentel Mateo‐Otero   +2 more
wiley   +1 more source

Mechanistic Prediction of Maternal, Fetal, and Amniotic Fluid Betamethasone Concentrations to Support Dosing Optimization in Pregnancy

The Journal of Clinical Pharmacology, Volume 66, Issue 10, October 2026.
Abstract Respiratory distress syndrome (RDS) remains a major cause of neonatal mortality following premature birth. Antenatal betamethasone is the standard of care to accelerate fetal lung maturation and improve neonatal outcomes; however, current dosing recommendations assume uniform maternal and fetal exposure across pregnancies. Gestational age (GA)‐
Alaa Mahdi, Khaled Abduljalil, Fernanda de Lima Moreira, Hiral Raju Mehta, Jhohann Richard de Lima Benzi, Alessandra Cristina Marcolin, Stephan Schmidt, Natalia V. de Moraes   +7 more
wiley   +1 more source

Global Proteomic Analysis of Sperm and Seminal Plasma From Tropically‐Adapted Rams With Contrasting Parameters of Frozen‐Thawed Semen

Molecular Reproduction and Development, Volume 93, Issue 10, October 2026.
ABSTRACT The aim of this study was to characterize the proteome of sperm and seminal plasma (SP) from rams with high semen freezability (HF) and low semen freezability (LF). Eleven ejaculates were collected from 12 rams, at 3‐day intervals, and cryopreserved (132 semen samples).
Wallisson Bruno de Morais Pacheco, Iran Aguila Maciel, Suane Santos Alves dos Santos, Alan Martins de Araújo, Francisca Nágila Matos Almeida, Denise Damasceno Guerreiro, Sheheryar Sheheryar, Lais Lacerda Brasil de Oliveira, Felipe Domingos de Sousa, Mohibullah Shah, Maria Elisabete Amaral Moraes, Carlos Roberto Koscky Paier, Ana Cristina de Oliveira Monteiro, Carminda Sandra Brito Salmito‐Vanderley, Arlindo A. Moura   +14 more
wiley   +1 more source

Ecotoxicological Insights From Ex Vivo Exposure of Whole Blood to PFOS and Glyphosate: Oxidative Stress and Immune Disruption

Environmental Toxicology, Volume 41, Issue 10, Page 1097-1104, October 2026.
ABSTRACT This study investigated the immunomodulatory effects of PFOS and glyphosate (GLY), both individually and in combination, on the whole blood of three ruminant species (cow, goats, and sheep) exposed ex vivo to environmentally relevant concentrations. The research focused on key biomarkers of oxidative stress (MDA), inflammation (myeloperoxidase
Francesco Molinari, Gianluca Antonio Franco, Francesca Inferrera, Nicla Tranchida, Antonella Iaconis, Maria Rizzo, Giuseppe Piccione, Enrico Gugliandolo, Davide Di Paola   +8 more
wiley   +1 more source

Long‐Term Outcomes of Omniflow II and BioIntegral Xenografts for Open Aortic Reconstruction in Predominantly Infected Settings: A Multicenter Cohort Study

World Journal of Surgery, Volume 50, Issue 10, Page 3129-3137, October 2026.
Evidence surrounding conduit selection for open in situ aortic reconstruction remains limited, particularly for xenograft use in infected settings. We evaluated long‐term outcomes after open aortic and aorto‐iliac reconstruction using BioIntegral No‐React bovine grafts and Omniflow II biosynthetic grafts in patients unsuitable for autologous vein ...
Tijmen W. Kraai, Eline I. Reinders Folmer, Barzi Gareb, David J. Liesker, Ben R. Saleem, Clark J. Zeebregts, Vascular Xenograft Research Group   +6 more
wiley   +1 more source