Results 161 to 170 of about 66,023 (384)

Reducing Unnecessary and Duplicate Ordering for Ovum and Parasite Examinations and Clostridium difficile PCR in Immunocompromised Patients by Using an Alert at the Time of Request in the Order Management System

open access: yesJournal of Clinical Microbiology, 2015
C. Otto   +10 more
semanticscholar   +1 more source

Allergic Reactivity and Memory Occur Independently of Sequential Switching Through IgG1

open access: yesAllergy, EarlyView.
Sequential switching through IgG1 is not required to produce IgE with sufficient allergen‐binding affinity to cause anaphylaxis against food allergens. Sequential switching through IgG1 does not confer a competitive advantage to become an IgE‐expressing cell.
Joshua F. E. Koenig   +11 more
wiley   +1 more source

BLOC1S1 Control of Vacuolar Organelle Fidelity Modulates Murine TH2 Cell Immunity and Allergy Susceptibility

open access: yesAllergy, EarlyView.
Abbreviations: BLOC1S1, biogenesis of lysosome organelles complex 1 subunit 1; cGAS, cyclic GMP‐AMP synthase; GATA3, GATA binding protein 3; IgE, immunoglobulin E; IKK, inhibitor of nuclear factor kappa‐B kinase; IL, interleukin; mtDNA, mitochondrial DNA; NF‐κB, nuclear factor‐kappa B; OVA, ovalbumin; MC903, vitamin D3 analog; STING, stimulator of ...
Rahul Sharma   +8 more
wiley   +1 more source

Asthma Alleviation by Ginsenoside Rb1 via Promotion of Treg Proliferation and Inflammatory T Cell Inhibition

open access: yesAllergy, EarlyView.
Screening of 250 natural products identified ginsenoside Rb1 (gRb1) as a potent modulator of regulatory T cells (Tregs) and inflammatory T cells. gRb1 increased IL‐10‐ and TGF‐β‐expressing Tregs while reducing Th17, Th1, and Th2 populations in both asthma model mice and human PBMCs.
Susanna Choi   +14 more
wiley   +1 more source

IFNγ Signaling Impairs Regulatory B Cell Function Resulting in Worse Control of Esophageal Food Allergy

open access: yesAllergy, EarlyView.
We used patient samples and a murine model to understand the contribution of Bregs to EoE immunopathology. We find that Breg‐derived IL‐10 is important for controlling EoE, but that Breg expansion and function are impaired in this condition. We identify IFNγ as a key negative regulator of Breg function in mice and patients with EoE. Bregs, regulatory B
Rachel L. Clement   +4 more
wiley   +1 more source

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