Results 111 to 120 of about 1,912,278 (288)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Conservation Letters, 2019 Biodiversity conservation requires space where conservation measures are implemented for a desired purpose. Setting land aside for conservation has been widely applied, while novel conservation modes (private–public partnerships, private multipurpose ...
Oliver Schöttker, Maria João Santos
doaj +1 more source
Waste management companies in Europe 2009 [PDF]
, 2010 This paper examines the ownership, employment and finances of the major waste companies in Europe, and recent developments in ...
Hall, David
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
CONSTITUTIONAL FOUNDATIONS OF THE PROPERTY RIGHTS OF CITIZENS AND ORGANIZATIONS FOR REAL ESTATE
Russian Journal of Economics and Law, 2015 Objective: to develop a comprehensive scientific conception of the constitutional foundations of the property rights of citizens and organizations for real estate.
Z. K. Kondratenko
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A Liberal Enchanted by Socialism? The Issue of Ownership in Neoliberal Doctrine of Ferdinand Zweig
Studia Historiae Oeconomicae, 2020 Ferdinand Zweig, who seems to be forgotten today, was one of the most eminent representatives of the so-called "Cracow School," an influential circle of economists associated with the Jagiellonian University.
Przemysław Pluciński +1 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
TRANSACTION COSTS OF THE CONCESSION AGREEMENT AS FORMS OF STATE-PRIVATE PARTNERSHIP
Вестник университета, 2017 The author of the article investigates the concession mechanism of public-private partnership, as well as transaction costs arising during the implementation of the concession project from the decision of the concluding member to conclude an agreement ...
A. Boldyrev
doaj
The Distribution of Ownership in an Apartment Ownership or Condominium Scheme [PDF]
, 2005 This is a preprint of an article that appeared in: 2002 Georgia Journal of International and Comparative Law, pp.
Merwe, Cornelius van der
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