Results 81 to 90 of about 626,054 (262)

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Przemiany w sposobie rozumienia prawa własności. Przejście z ujęcia absolutnego do przyjęcia ograniczonego i prospołecznego charakteru tego prawa

open access: yesActa Iuris Stetinensis, 2016
The article concerns the changes in the content and in the way of understanding of ownership that occurred from the period of antiquity. Initially, it was considered inviolable right of ownership, exclusive and unlimited.
Adam Banaszkiewicz
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Ownership and High-Growth Firms [PDF]

open access: yes
Empirical studies demonstrate that most net job-growth originates from a small number of high-growth firms (HGFs). The purpose of this paper is to analyze whether firm ownership – family, or private non-family – matters for being a HGF, using data ...
Johansson, Dan   +2 more
core  

Easement or public land? An economic analysis of different ownership modes for nature conservation measures in California

open access: yesConservation Letters, 2019
Biodiversity conservation requires space where conservation measures are implemented for a desired purpose. Setting land aside for conservation has been widely applied, while novel conservation modes (private–public partnerships, private multipurpose ...
Oliver Schöttker, Maria João Santos
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Ownership Concentration, Corporate Governance and Firm Performance: Evidence from Pakistan [PDF]

open access: yes
The study investigates the determinants of ownership concentration, the effect of ownership concentration on the firm’s performance with the sample of sixty representativ e firms from different manufacturing sectors of the Pakistan’s economy during 2003 ...
Attiya Y. Javid, Robina Iqbal
core  

CONSTITUTIONAL FOUNDATIONS OF THE PROPERTY RIGHTS OF CITIZENS AND ORGANIZATIONS FOR REAL ESTATE

open access: yesRussian Journal of Economics and Law, 2015
Objective: to develop a comprehensive scientific conception of the constitutional foundations of the property rights of citizens and organizations for real estate.
Z. K. Kondratenko
doaj  

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