Results 131 to 140 of about 259,578 (273)

The protective effects of aloperine against ox-LDL-induced endothelial dysfunction and inflammation in HUVECs

Artificial Cells Nanomedicine and Biotechnology, 2020
Atherosclerosis is a potentially life-threatening cardiovascular disease characterized by chronic endothelial inflammation and the formation of atherosclerotic lesions. Circulating ox-LDL is known to induce atherosclerosis by triggering oxidative stress,
Weiwei Li, Yanshu Li, Yi Zhao, Lina Ren
semanticscholar   +1 more source

From Adipose Tissue to Cardiac Repair: Extracellular Vesicles in Cardiovascular Regeneration

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Adipose‐derived extracellular vesicles (ADEVs) secreted by adipose tissue have gained increasing attention due to their regenerative and immunomodulatory properties in cardiovascular diseases. They carry proteins, lipids, and nucleic acids that mediate intercellular communication and influence cardiac pathophysiology. In atherosclerosis, ADEVs
Karolina Ignaczak, Pola Ochocka, Karol Sadowski, Weronika Ploch, Dominika Tomkiel, Mariusz Tomaniak, Wioletta Olejarz   +6 more
wiley   +1 more source

Sialidase Neu3 Induced Sialic Acid Disorder and Promoted Vascular Endothelial Injury Through Transcription Factor SP3

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Atherosclerotic cardiovascular disease is still a major cause for the increasing mortality worldwide. The elevated metabolite N‐acetylneuraminic acid (Neu5Ac) was considered one of the important risk factors responsible for the initiation of endothelial impairment, then participated in atherosclerosis progression.
Yining Lu, Peng Xiang, Qingqiu Chen, Xianmin Wang, Le Chen, Tongchuan Wang, Rong Hu, Limei Ma, Chao Yu   +8 more
wiley   +1 more source

Increased Serum ox-LDL Levels Correlated with Lung Function, Inflammation, and Oxidative Stress in COPD

Mediators of Inflammation, 2013
Chronic obstructive pulmonary disease (COPD) is associated with abnormal inflammation and high oxidative stress. Studies suggest that oxidized low density lipoprotein (ox-LDL) is involved in diseases associated with oxidative stress and inflammation ...
Yongchun Shen, Ting Yang, Shujin Guo, Xiao'ou Li, Lei Chen, Tao Wang, Fuqiang Wen   +6 more
doaj   +1 more source

RETRACTED: Oxidized LDL Causes Endothelial Apoptosis by Inhibiting Mitochondrial Fusion and Mitochondria Autophagy

Frontiers in Cell and Developmental Biology, 2020
Oxidized low-density lipoprotein (ox-LDL)-induced endothelial dysfunction is an initial step toward atherosclerosis development. Mitochondria damage correlates with ox-LDL-induced endothelial injury through an undefined mechanism. We explored the role of
Jia Zheng, Chengzhi Lu
doaj   +1 more source

Oxidized Low-Density Lipoprotein Induces Reactive Oxygen Species-Dependent Proliferation of Intestinal Epithelial Cells

Pharmaceuticals
Background/Objectives: Oxidized low-density lipoprotein (ox-LDL) is a proinflammatory particle associated with various diseases and affects cell proliferation and viability in multiple cell types.
Eddy E. Gonzalez-Horta, Juan F. Burgueno, María J. Leiva, Carla Villavicencio, Fernando I. Kawaguchi, Hajar Hazime, Fátima Reyes, Viana Manrique-Suárez, Natalie C. Parra, Maria T. Abreu, Jorge R. Toledo   +10 more
doaj   +1 more source

Okside-LDL ve Reseptörü Lektin Benzeri Ox-LDL Reseptör-1

Genel Tıp Dergisi, 2016
Oksidatif stres fazla oksidant bileşiğin yapılması ve antioksidant koruma mekanizmasının azlığı sonucu oluşarak doku hasarlarına yol açar. Oksidatif stres sonucu oluşan okside-düşük dansiteli lipoprotein oxidized low-density lipoprotein ox-LDL ...
Ümmügülsüm Can
doaj  

Isolation of macrophage-like cell mutants resistant to the cytotoxic effect of oxidized low density lipoprotein

Journal of Lipid Research, 1998
A high concentration of oxidized low density lipoprotein (Ox-LDL) showed a cytotoxic effect on mouse macrophage-derived J774 cells. Mutant cells were selected from these cells that were resistant to the cytotoxic effect of Ox-LDL.
Hideki Hakamata, Akira Miyazaki, Masakazu Sakai, Hirofumi Matsuda, Hiroshi Suzuki, Tatsuhiko Kodama, Seikoh Horiuchi   +6 more
doaj   +1 more source

Hypoxia in atherogenesis [PDF]

, 2016
The anoxemia theory proposes that an imbalance between the demand for and supply of oxygen in the arterial wall is a key factor in the development of atherosclerosis.
Creemers EE, Gordon A. A. Ferns, Ismail S, Jain MR, Lamia Heikal, Lv G, Mita T, Pedersen SF, Zhang M, Zhong J   +9 more
core   +1 more source

Exosome-encapsulated miR-505 from ox-LDL-treated vascular endothelial cells aggravates atherosclerosis by inducing NET formation.

Acta Biochimica et Biophysica Sinica, 2019
Neutrophil extracellular traps (NETs) play an important role in the pathological process of atherosclerosis (AS). This study aims to evaluate whether exosomes from oxidized low-density lipoprotein (ox-LDL)-treated vascular endothelial cells (VECs ...
Li Chen, Li-qun Hu, Qing Li, Jian Ma, Hongqi Li   +4 more
semanticscholar   +1 more source