Results 231 to 240 of about 32,424 (300)

Biocatalytic synthesis of oxa(thia)diazole aryl thioethers. [PDF]

open access: yesSci Rep
Mottaghi Amlashi D   +5 more
europepmc   +1 more source

Discovery, lead identification and exploration of potential oxadiazole derivatives in targeting STAT3 as anti-cancer agents. [PDF]

open access: yesIn Silico Pharmacol
Panwar V   +7 more
europepmc   +1 more source

Difluoromethyl-1,3,4-oxadiazoles Are Selective, Mechanism-Based, and Essentially Irreversible Inhibitors of Histone Deacetylase 6.

Journal of Medicinal Chemistry, 2023
Histone deacetylase 6 (HDAC6) is an important drug target in oncological and non-oncological diseases. Most available HDAC6 inhibitors (HDAC6i) utilize hydroxamic acids as a zinc-binding group, which limits therapeutic opportunities due to its genotoxic ...
Beate König   +6 more
semanticscholar   +1 more source

A comprehensive review of recent advances in the biological activities of 1,2,4‐oxadiazoles

Archiv der Pharmazie, 2022
Nitrogen heterocycles play an essential role in medication development. The 1,2,4‐oxadiazole heterocycle has been extensively studied, yielding a large variety of molecules with varied biological functions.
O. Hendawy
semanticscholar   +1 more source

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