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Synthesis, antibacterial activity and in silico study of new bis(1,3,4-oxadiazoles)

Synthetic Communications, 2022
In the current study, new bis(2,5-disubstituted 1,3,4-oxadiazoles) linked to aliphatic cores were efficiently prepared. For this purpose, the appropriate bis(aldehydes) and benzohydrazides were reacted to produce the corresponding bis(N-benzoylhydrazones)
A. Abdelfattah   +2 more
semanticscholar   +1 more source

Potential Synthetic Routes and Metal-Ion Sensing Applications of 1,3,4-Oxadiazoles: An Integrative Review

Critical reviews in analytical chemistry, 2022
Oxadiazoles, especially 1,3,4-oxadiazole scaffolds, stand among the foremost heterocyclic fragments with a broad spectrum of applications in diverse fields, including pharmacology, polymers, material science, and organic electronics, among others.
D. Sharma, H. Om, A. Sharma
semanticscholar   +1 more source

Design, Synthesis and Antimicrobial Behaviors of Novel Oxadiazoles Owning Various N-Containing Heterocyclic Pendants.

Pest Management Science, 2020
BACKGROUND The gradually elevated outbreak of plant bacterial diseases severely limits agricultural products and small amounts of pesticides can manage them.
Dan Zeng   +6 more
semanticscholar   +1 more source

Two antioxidant 2,5-disubstituted-1,3,4-oxadiazoles (CoViTris2020 and ChloViD2020): successful repurposing against COVID-19 as the first potent multitarget anti-SARS-CoV-2 drugs

, 2020
Repurposing of known drugs and compounds as anticoronavirus disease 2019 (anti-COVID-19) agents through biological reevaluation of their activities, specially the antisevere acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) activities, is a new ...
A. Rabie
semanticscholar   +1 more source

Perfluoro-1,3,4-oxadiazoles

Journal of Fluorine Chemistry, 1992
Abstract Some new polyfluorinated 1,3,4-oxadiazoles have been obtained via a two-step method. The cycloadditions of the 1,3,4-oxadiazoles have been studied and an analysis of the energies of the frontier orbitals calculated by the MNDO method indicates a LUMO-dependent pathway for cycloaddition.
N.V. Vasiliev   +3 more
openaire   +1 more source

Banana-Shaped 1,2,4-Oxadiazole Analogues of 1,3,4-Oxadiazoles

Molecular Crystals and Liquid Crystals Science and Technology. Section A. Molecular Crystals and Liquid Crystals, 2001
Abstract In the last years bent banana-shaped mesomorphic molecules found an increasingly great interest among theoreticians and experimentalists due to the nature of this type of liquid crystals to exhibit a spontaneous polarization in the absence of any chiral group in the molecules.
S. I. TORGOVA   +3 more
openaire   +2 more sources

Bioisosterism: 1,2,4‐Oxadiazole Rings

ChemMedChem, 2023
AbstractAlthough studies in drug discovery have gained momentum in recent years, the conversion of drugs in use today into less toxic derivatives with pharmacologically superior properties is still of great importance in drug research. Bioisosterism facilitates the conversion of drugs into derivatives that present more positive pharmacological and ...
Merve Camci, Nilgün Karali
openaire   +2 more sources

Synthesis and In Vitro and In Vivo Biological Activity Evaluation and Quantitative Proteome Profiling of Oxadiazoles Bearing Flexible Heterocyclic Patterns.

Journal of Agricultural and Food Chemistry, 2019
A novel series of simple 1,3,4-oxadiazoles that bear flexible heterocyclic patterns was prepared, and their biological activities in plant pathogenic bacteria, fungi, oomycetes, and Meloidogyne incognita in vitro and in vivo were screened to explore low ...
Qing-Qing Tao   +9 more
semanticscholar   +1 more source

1,2,4‐Oxadiazoles

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +1 more source

1,2,5-Oxadiazoles

ChemInform, 1996
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +1 more source

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