Results 251 to 260 of about 32,424 (300)

Batch Versus Flow Lithiation-Substitution of 1,3,4-Oxadiazoles: Exploitation of Unstable Intermediates Using Flow Chemistry.

Chemistry, 2019
1,3,4-Oxadiazoles are a common motif in pharmaceutical chemistry, but few convenient methods for their modification exist. A fast, convenient, high yielding and general α-substitution of 1,3,4-oxadiazoles has been developed using a metalation ...
J. Wong, J. Tobin, F. Vilela, G. Barker
semanticscholar   +1 more source

Poly‐1,3,4‐oxadiazoles. I. Polyphenylene‐1,3,4‐oxadiazoles

Journal of Polymer Science Part A: General Papers, 1965
AbstractPolyphenylene‐1,3,4‐oxadiazoles have been prepared from benzenedicarboxylic acids or their derivatives and hydrazine by solution polycondensation in fuming sulfuric acid or polyphosphoric acid. These polymers were characterized by good thermal stability, and the molecular weights attained were high enough for the products to exhibit fiber‐or ...
Yoshio Iwakura, Keikichi Uno, Shigeyoshi Hara   +2 more
openaire   +1 more source

Novel 1,3,4-oxadiazoles as antitubercular agents with limited activity against drug-resistant tuberculosis.

Future Medicinal Chemistry, 2019
AIM In recent times, heterocyclic chemotypes are being explored for the development of new antimycobacterials that target the drug-resistant tuberculosis.
Vitthal B. Makane, V. Krishna, E. V. Krishna, Manjulika Shukla, B. Mahizhaveni, S. Misra, S. Chopra, D. Sriram, Vijayan N Azger Dusthackeer, H. Rode   +9 more
semanticscholar   +1 more source

Banana-shaped 1,2,4-oxadiazoles

Pramana, 2003
3,5-Disubstituted 1,2,4-oxadiazoles are a new type of liquid crystalline (LC) compounds with asymmetrical five-membered heterocycle as a central unit. They have a bent shape and are very convenient model-compounds for studying the dependence of the LC properties on the molecular design.
S. I. TORGOVA, T. A. GEIVANDOVA, O. FRANCESCANGELI, STRIGAZZI, Alfredo   +3 more
openaire   +2 more sources

Oxadiazoles in Medicinal Chemistry

Journal of Medicinal Chemistry, 2012
Oxadiazoles are five-membered heteroaromatic rings containing two carbons, two nitrogens, and one oxygen atom, and they exist in different regioisomeric forms. Oxadiazoles are frequently occurring motifs in druglike molecules, and they are often used with the intention of being bioisosteric replacements for ester and amide functionalities.
Jonas, Boström, Anders, Hogner, Antonio, Llinàs, Eric, Wellner, Alleyn T, Plowright   +4 more
openaire   +2 more sources

Oxidative Cyclization Protocol for the Preparation of Energetic 3-Amino-5- R-1,2,4-oxadiazoles.

Organic Letters, 2018
An efficient method has been developed for the synthesis of energetic 3-amino-5- R-1,2,4-oxadiazoles via iodobenzene diacetate (IBD)-mediated oxidative cyclization in high yields at ambient temperature.
Yongxing Tang, Gregory H. Imler, D. Parrish, J. Shreeve   +3 more
semanticscholar   +1 more source

Poly‐1,3,4‐oxadiazoles. III. Alicyclic poly‐1,3,4‐oxadiazoles

Die Makromolekulare Chemie, 1966
AbstractSome alicyclic poly‐1,3,4‐oxadiazoles were prepared from cycloalkanedicarboxylic dihydrazides or from cycloalkanedicarboxylic acids and hydrazine sulfate by solution polycondensation in polyphosphoric acid. These polymers were characterized by high melting temperature.
Yoshio Iwakura, Keikichi Uno, Shigeyoshi Hara   +2 more
openaire   +1 more source

Oxadiazoles

2011
Romeo G, CHIACCHIO, Ugo
  +6 more sources

Infrared spectra of 1,3,4-oxadiazole and 2,5,-dimethyl-1,3,4-oxadiazole. Vibrational assignment of 1,3,4-oxadiazole

Journal of Molecular Spectroscopy, 1967
Abstract The infrared absorption spectrum of 1,3,4-oxadiazole has been recorded in the region 5000-400 cm −1 in the vapor and in the liquid phases, in CS 2 and C 2 Cl 4 solutions. Also, the infrared absorption spectrum of liquid 2,5-dimethyl-1,3,4-oxadiazole was recorded in the same region. A tentative assignment of the fundamental vibrations of 1,
Daniel Højgaard Christensen, Jørgen Tormod Nielsen, Ole Faurskov Nielsen   +2 more
openaire   +1 more source

Poly‐1, 3,4‐oxadiazoles. II. Aliphatic poly‐1,3,4‐oxadiazoles

Die Makromolekulare Chemie, 1966
AbstractAliphatic poly‐1,3,4‐oxadiazoles were prepared from aliphatic dicarboxylic dihydrazides or from dicarboxylic derivatives and hydrazine sulfate by solution polycondensation in polyphosphoric acid. Their preparation and physical properties, such as solubility, crystallinity, and thermal stability are described.
Yoshio Iwakura, Keikichi Uno, Shigeyoshi Hara   +2 more
openaire   +1 more source