Results 281 to 290 of about 30,682 (325)
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Synthesis and Antineoplastic Evaluation of Novel Unsymmetrical 1,3,4-Oxadiazoles.
Journal of Medicinal Chemistry, 2016A series of novel 1,3,4-oxadiazoles was synthesized and evaluated for their cytotoxic activity in in vitro tumor models. Four of the new compounds (2d, 2j, 2k, and 2n) showed growth inhibition in the XTT dye assay.
V. Nieddu +7 more
semanticscholar +1 more source
2015
[288-37-9] C2H2N2O (MW = 70.050) InChI = 1S/C2H2N2O/c1-2-4-5-3-1/h1-2H InChIKey = JKFAIQOWCVVSKC-UHFFFAOYSA-N (small-molecule heterocyclic pharmacophore) Physical Data: bp 98 °C, mp −28 °C. Alternate Name: furazan. Handling: compound known to possess potent biological activities in humans; toxic by skin contact or ...
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[288-37-9] C2H2N2O (MW = 70.050) InChI = 1S/C2H2N2O/c1-2-4-5-3-1/h1-2H InChIKey = JKFAIQOWCVVSKC-UHFFFAOYSA-N (small-molecule heterocyclic pharmacophore) Physical Data: bp 98 °C, mp −28 °C. Alternate Name: furazan. Handling: compound known to possess potent biological activities in humans; toxic by skin contact or ...
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Journal of Organic Chemistry, 2015
2-Amino-substituted 1,3,4-oxadiazoles and 1,3,4-thiadiazoles were synthesized via condensation of semicarbazide/thiosemicarbazide and the corresponding aldehydes followed by I2-mediated oxidative C–O/C–S bond formation.
Pengfei Niu +7 more
semanticscholar +1 more source
2-Amino-substituted 1,3,4-oxadiazoles and 1,3,4-thiadiazoles were synthesized via condensation of semicarbazide/thiosemicarbazide and the corresponding aldehydes followed by I2-mediated oxidative C–O/C–S bond formation.
Pengfei Niu +7 more
semanticscholar +1 more source
Synthesis of 1,2,4‐Oxadiazoles
ChemInform, 2006AbstractFor Abstract see ChemInform Abstract in Full Text.
G. I. Gapparova, L. A. Kayukova
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, 2016
A convenient and efficient protocol has been developed for the synthesis of 1,2,4-triazoles, N-fused 1,2,4-triazoles and 1,2,4-oxadiazoles using molybdenum hexacarbonyl where, for the first time, molybdenum hexacarbonyl acts as a convenient and reliable ...
Mangarao Nakka +3 more
semanticscholar +1 more source
A convenient and efficient protocol has been developed for the synthesis of 1,2,4-triazoles, N-fused 1,2,4-triazoles and 1,2,4-oxadiazoles using molybdenum hexacarbonyl where, for the first time, molybdenum hexacarbonyl acts as a convenient and reliable ...
Mangarao Nakka +3 more
semanticscholar +1 more source
2015
[288-43-7] C2H2N2O (MW 70.06) InChI = 1S/C2H2N2O/c1-2-5-4-3-1/h1-2H InChIKey = WCPAKWJPBJAGKN-UHFFFAOYSA-N (1,5-electrocyclic ring opening3; 1,3-dipolar cycloaddition7 with alkynes and nitrous oxide)
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[288-43-7] C2H2N2O (MW 70.06) InChI = 1S/C2H2N2O/c1-2-5-4-3-1/h1-2H InChIKey = WCPAKWJPBJAGKN-UHFFFAOYSA-N (1,5-electrocyclic ring opening3; 1,3-dipolar cycloaddition7 with alkynes and nitrous oxide)
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Poly‐1,3,4‐oxadiazoles. III. Alicyclic poly‐1,3,4‐oxadiazoles
Die Makromolekulare Chemie, 1966AbstractSome alicyclic poly‐1,3,4‐oxadiazoles were prepared from cycloalkanedicarboxylic dihydrazides or from cycloalkanedicarboxylic acids and hydrazine sulfate by solution polycondensation in polyphosphoric acid. These polymers were characterized by high melting temperature.
Keikichi Uno +2 more
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Synthesis and antiproliferative efficiency of novel bis(imidazol-1-yl)vinyl-1,2,4-oxadiazoles
, 2016A new approach for the synthesis of novel bis(imidazol-1-yl)vinyl-1,2,4-oxadiazoles has been developed. This method operates in a single step giving the products in good to excellent yields.
K. Nandeesh +8 more
semanticscholar +1 more source
Mass spectrometric analysis of 1,2,4‐Oxadiazoles and 4,5‐Dihydro‐1,2,4‐Oxadiazoles
Mass Spectrometry Reviews, 2004Abstract1,2,4‐Oxadiazoles and 4,5‐dihydro‐1,2,4‐oxadiazoles are an interesting class of compounds because of their pharmacological and other properties. Although short descriptions of these compounds under mass spectrometric conditions exist, we thought it worthwhile to write a comprehensive review of this class of compounds.
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