Results 91 to 100 of about 123,392 (306)

Decoding RNA regulation: Challenges and opportunities for RNA‐based therapies in Europe

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract RNA‐based medicinal products represent a promising frontier in personalised medicine, offering sequence‐specific disease targeting at various molecular levels, yet their clinical translation in the European Union (EU) may be hindered by regulatory uncertainty around definitions and evidence requirements; this study therefore aims to identify ...
Olivia C. Lewis   +4 more
wiley   +1 more source

Oxygen Activation by Mononuclear Mn, Co, and Ni Centers in Biology and Synthetic Complexes [PDF]

open access: yes, 2017
The active sites of metalloenzymes that catalyze O2-dependent reactions generally contain iron or copper ions. However, several enzymes are capable of activating O2 at manganese or nickel centers instead, and a handful of dioxygenases exhibit activity ...
Fiedler, Adam T., Fischer, Anne A.
core   +1 more source

Establishment of a Single‐Cell Minimal Medium: A Case Study for Microfluidic Cultivation of Corynebacterium glutamicum

open access: yesBiotechnology and Bioengineering, EarlyView.
Conventional bulk media are often unsuitable for single‐cell cultivation and analysis because they provide excess nutrients or lack essential components. Redesigning the medium allows for controlled, defined growth, enabling the development of a robust minimal medium that supports quantitative and reproducible single‐cell analysis across different ...
Judith Wegmann   +5 more
wiley   +1 more source

Impact of Regular or Extended Hemodialysis and Hemodialfiltration on Plasma Oxalate Concentrations in Patients With End-Stage Renal Disease

open access: yesKidney International Reports, 2017
Calcium oxalate supersaturation is regularly exceeded in the plasma of patients with end-stage renal disease (ESRD). Previous reports have indicated that hemodialfiltration (HDF) lowers elevated plasma oxalate (POx) concentrations more effectively ...
Theresa Ermer   +10 more
doaj   +1 more source

Optimizing Pichia Pastoris Cell‐Free Protein Synthesis to Improve Economics

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Cell‐free protein synthesis (CFPS) is a powerful and versatile platform that supports a wide range of applications, from fundamental studies of the genetic code to scalable and rapid protein production. The recently developed Pichia pastoris CFPS combines advantages of both prokaryotic and eukaryotic systems, including a rapid growth rate ...
Rui Wu   +4 more
wiley   +1 more source

Diversity in biochemical traits among taro (Colocasia esculenta (L.) Schott) accessions in southwest Ethiopia: Insights for breeding and food security

open access: yesJournal of Agriculture and Food Research
Taro is among the underutilized root and tuber crops. It is a staple food in tropical and subtropical regions, including Ethiopia. Taro plays a crucial role in food security, nutrition, and income generation for small-scale farmers in southwest Ethiopia.
Ketema Balcha Debela   +3 more
doaj   +1 more source

Crystal structure of catena-poly[[aquadi-n-propyltin(IV)]-μ-oxalato]

open access: yesActa Crystallographica Section E, 2014
The title compound, [Sn(C3H7)2(H2O)(C2O4)]n, represents the first diorganotin(IV) oxalate hydrate to be structurally characterized. The tin(IV) atom of the one-dimensional coordination polymer is located on a twofold rotation axis and is coordinated by ...
Martin Reichelt, Hans Reuter
doaj   +1 more source

Responses of ectomycorrhizal fungi to mineral substrates [PDF]

open access: yes, 2003
Boreal forest soils are complex, heterogeneous growth substrates where organic and mineral components provide nutrient resources for soil organisms and plants. Mineral nutrients are cycled between living and dead organic components of the forest soil and
Rosling, Anna
core  

Thermodynamic Evaluation of Dual Substrate Growth

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Various C₁–C₂ compounds are increasingly available through electrochemical reduction of CO2. Although not always suitable as a sole substrate, these compounds can supplement a primary substrate like glucose to enhance microbial growth. Yet, the mechanisms underlying the effects of dual substrate consumption on growth rate and growth yield ...
Marit A. Verheijen   +3 more
wiley   +1 more source

In-vitro analysis of the anticoagulation properties of Kamias (Averrhoa Bilimbi)

open access: yesJournal of Allied Health Sciences & Medical Research
This study investigated the potential of Averrhoa bilimbi (kamias) extract as a novel anticoagulant and compared its efficacy with the commercially available anticoagulant potassium oxalate.
Rizza R. Ballesteros   +2 more
doaj   +1 more source

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