Tratamento da esquistossomose com oxamniquine (xarope) em crianças
Foram tratados pela oxamniquine, sob a forma de xarope, 75 esquistossomôticos. com idade de 3 a 12 anos, distribuídos uniformente por quatro grupos, utilizando-se os esquemas de 15, 20 e 25 mg por quilo de peso corporal, em dose única e 20mg subdivididos
J. C. Bina, A. Prata
doaj +3 more sources
Eficácia terapêutica da oxamniquine oral no tratamento da salmonelose septicêmica prolongada
Trinta e cinco pacientes com salmonelose septicêmica prolongada (SSP) foram selecionados para o estudo. Vinte (Grupo 1), foram tratados com a oxamniquine oral (15-20mg/kg de peso, dose única) e 15 (Grupo 2) com o cloranfenicol (50mg/kg de peso/15-20 dias)
José Roberto Lambertucci+4 more
doaj +1 more source
Antibody reactivity against potato apyrase, a protein that shares epitopes with Schistosoma mansoni ATP diphosphohydrolase isoforms, in acute and chronically infected mice, after chemotherapy and reinfection [PDF]
Schistosoma mansoni ATP diphosphohydrolase isoforms and potato apyrase share conserved epitopes. By enzyme-linked immunosorbent assays, elevated levels of IgM, IgG2a and IgG1 antibody reactivity against potato apyrase were observed in S. mansoni-infected
Alexandre Arthur Jacinto+28 more
core +3 more sources
Oxamniquine for treating Schistosoma mansoni infection in Sudan. [PDF]
The efficacy and acceptability of oral oxamniquine were assessed in Sudanese patients infected with Schistosoma mansoni. Cure rates, determined by the absence of viable eggs in the stools six months after treatment, were 94.9% in patients treated with a total of 60 mg/kg, 78.8% in patients treated with 40 mg/kg, and 68.9% in patients treated with 30 mg/
openaire +3 more sources
The immune-dependence of chemotherapy in experimental schistosomiasis
Experimental evidence indicates that immune effector mechanisms can enhance the activity of schistosomicidal drugs. Praziquantel, oxamniquine, hycanthone and antimony were less effective against Schistosoma mansoni infections in mice immunosuppressed by ...
M. J. Doenhoff
doaj +1 more source
Praziquantel, Oxamniquine, and Metrifonate in the Treatment of Schistosomiasis in Riyadh
This study sought to compare the effectiveness and side effects of praziquantel versus oxamniquine in treating 200 patients with Schistosoma mansoni infection and praziquantel versus metrifonate in...
Suliman R. Al-Balla+7 more
openaire +2 more sources
Patients with acute schistosomiasis were studied before and after oxamniquine treatment. They had been exposed to cercariae 5 to 9 weeks before, and presented compatible clinical manifestations, eosinophilia, and high levels of total IgE.
Joelma R de Souza+8 more
doaj
Uptake of [14C]oxamniquine by Schistosoma mansoni
The uptake and retention of drug-related material by Schistosoma mansoni was studied in the mouse host following a single oral or intramuscular does (50 mg/kg) of [14C]oxamniquine. Male worms took up more labelled material than did female worms but the amount in each particular sex of worm was found to be similar after both routes of administration ...
B. Kaye, N. M. Woolhouse
openaire +3 more sources
Clustered Regularly Interspaced Short Palindromic Repeats/ CRISPR associated protein 9-mediated editing of Schistosoma mansoni genes: Identifying genes for immunologically potent drug and vaccine development. [PDF]
Naidoo P, Mkhize-Kwitshana ZL.
europepmc +1 more source
Ultrasonographic assessment of urinary tract lesions due to Schistosoma haematobium in Niger after four consecutive years of treatment with praziquantel [PDF]
Une étude comparative sur l'étendue des lésions du tractus urinaire détectées par échographie a été entreprise dans 2 villages du Niger situés près de périmètres irrigués.
Develoux, M.+4 more
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