Results 61 to 70 of about 1,461 (168)
Com o objetivo de se estudar a ação da oxamniquine, uma droga utilizada no tratamento da esquistossomose, sobre a cromatina de núcleos de células animais, foram estudados os padrões de basofilia e anisotropia nucleares em hepatócitos, em células do ...
Ivanira José Bechara +1 more
doaj
Oxamniquine, praziquantel and lovastatin association in the experimental Schistosomiasis mansoni
The activity of lovastatin associated with oxamniquine or praziquantel against schistosomiasis mansoni was evaluated in mice infected with Schistosoma mansoni.
Neusa Araújo +4 more
doaj +1 more source
Drug development for neglected diseases: a deficient market and a public-health policy failure. [PDF]
There is a lack of effective, safe, and affordable pharmaceuticals to control infectious diseases that cause high mortality and morbidity among poor people in the developing world.
Anderson +32 more
core +1 more source
Convulsão associada ao uso de Oxamniquine: relato de um caso
Os autores apresentam um caso de convulsão associada ao uso de oxamniquine, comentando sobre a necessidade de se adquirir mais segurança no manuseio da droga, antes de se recomendar o seu emprego em massa.The authors report a case of convulsion in the ...
J. C. Bina, A. Spínola
doaj +3 more sources
Stability of Schistosoma mansoni progeny to antischistosomal drugs
The susceptibility of the MAP Brazilian strain (F1 to F5 progenies) of S. mansoni to four antischistosomal drugs has been reported in a previous study. In the present investigation, progeny F14 of the same strain, was tested for stability to the same 4 ...
Luiz Candido de Souza Dias +1 more
doaj +1 more source
Association of oxamniquine praziquantel and clonazepam in experimental Schistosomiasis mansoni
The antischistosomal activity of clonazepam, when administered alone or in association with oxamniquine and praziquantel, was experimentally evaluated in mice infected with Schistosoma mansoni.
Neusa Araujo +3 more
doaj +1 more source
Технология опытного производства тетрагидрохинолина: (3aS*,4R*)-4-циано-1,2,3,3а,4,5-гексагидро-1Н-пирроло[1,2-а]хинолин-4-карботиоамида [PDF]
Received: 17.07.2016; accepted: 24.29.2016; published: 01.12.2016.Поступило: 17.07.2016; приянято: 24.09.2016; опубликовано: 01.12.2016.The regulations of the pilot production of (3aS*,4R*)-4-cyano-1,2,3,3а,4,5-hexahydro-1Н-pyrrolo[1,2-а]quinoline-4 ...
Platonova, A. Yu. +3 more
core +1 more source
Schistosoma mansoni: structural damage after treatment with oxamniquine [PDF]
The effects of a single dose (100 mg/kg-body weight of mouse) of oxamniquine on the worm's tegument and paranchyma in relation to the process of immunological granulomatous reaction of the host's liver are described under light and electron microscopy (EM). The lesions caused by the drug are sequentially and simultaneously described in form of swelling,
Magalhães Filho, Ageu +3 more
openaire +4 more sources
Campbell Systematic Reviews, Volume 9, Issue 1, Page 1-41, 2013.
Vivian Welch +9 more
wiley +1 more source
Um total de 54 pacientes adultos, com esquistossomose mansônica crônica, nas formas intestinal ou hepatintestinal, participou de um ensaio clínico duplo-cego, para comparar o praziquantel com a oxamniquine.
Aloisio Sales da Cunha +1 more
doaj +1 more source

