Results 51 to 60 of about 709 (171)
Tratamento da esquistossomose com oxamniquine (xarope) em crianças
Revista da Sociedade Brasileira de Medicina Tropical, 1975 Foram tratados pela oxamniquine, sob a forma de xarope, 75 esquistossomôticos. com idade de 3 a 12 anos, distribuídos uniformente por quatro grupos, utilizando-se os esquemas de 15, 20 e 25 mg por quilo de peso corporal, em dose única e 20mg subdivididos
J. C. Bina, A. Prata
doaj +3 more sources
Eficácia terapêutica da oxamniquine oral no tratamento da salmonelose septicêmica prolongada
Revista do Instituto de Medicina Tropical de São Paulo, 1985 Trinta e cinco pacientes com salmonelose septicêmica prolongada (SSP) foram selecionados para o estudo. Vinte (Grupo 1), foram tratados com a oxamniquine oral (15-20mg/kg de peso, dose única) e 15 (Grupo 2) com o cloranfenicol (50mg/kg de peso/15-20 dias)
José Roberto Lambertucci +4 more
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Memorias do Instituto Oswaldo Cruz, 2007 Patients with acute schistosomiasis were studied before and after oxamniquine treatment. They had been exposed to cercariae 5 to 9 weeks before, and presented compatible clinical manifestations, eosinophilia, and high levels of total IgE.
Joelma R de Souza +8 more
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Parasites & Vectors, 2018 Background Schistosomiasis is one of the most harmful parasitic diseases worldwide, praziquantel being the only drug in widespread use to treat it. We recently demonstrated that ferrocenyl, ruthenocenyl and benzyl derivatives of oxamniquine (Fc-OXA, Rc ...
Valentin Buchter +3 more
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Physicochemical interactions of praziquantel, oxamniquine and tablet excipients
Journal of Pharmacy and Pharmacology, 1992 Abstract A differential scanning calorimetry and infrared spectrophotometry study of potential interactions between oxamniquine and praziquantel, two synergistic anti-parasitic drugs, indicated that they did not interact on fusion.
R J, Prankerd, S M, Ahmed
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The immune-dependence of chemotherapy in experimental schistosomiasis
Memorias do Instituto Oswaldo Cruz, 1989 Experimental evidence indicates that immune effector mechanisms can enhance the activity of schistosomicidal drugs. Praziquantel, oxamniquine, hycanthone and antimony were less effective against Schistosoma mansoni infections in mice immunosuppressed by ...
M. J. Doenhoff
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PLOS Neglected Tropical Diseases, 2015 For over two decades, a racemic mixture of oxamniquine (OXA) was administered to patients infected by Schistosoma mansoni, but whether one or both enantiomers exert antischistosomal activity was unknown. Recently, a ~30 kDa S. mansoni sulfotransferase (SmSULT) was identified as the target of OXA action.Here, we separate the OXA enantiomers using ...
Taylor A B +12 more
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Bulletin of the World Health Organization, 2003 OBJECTIVE: To evaluate the therapeutic efficacy of oxamniquine and praziquantel, the two most clinically important schistosomicide drugs, and to compare the accuracy of faecal examination with the accuracy of oogram in testing for Schistosoma mansoni ...
Ferrari M.L.A. +4 more
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Clustered Regularly Interspaced Short Palindromic Repeats/ CRISPR associated protein 9-mediated editing of Schistosoma mansoni genes: Identifying genes for immunologically potent drug and vaccine development. [PDF]
Rev Soc Bras Med Trop, 2022 Naidoo P, Mkhize-Kwitshana ZL.
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Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis. [PDF]
PLoS Pathog, 2023 Alwan SN +5 more
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