Results 41 to 50 of about 1,239 (187)

Schistosomiasis‐Associated Pulmonary Hypertension

Pulmonary Circulation, Volume 4, Issue 4, Page 596-611, December 2014., 2014
Schistosomiasis, a parasite‐borne disease, is highly prevalent in Africa and Asia; it is estimated that close to 20 million people worldwide have a severe form of the disease. The chronic form can affect the gastrointestinal system and lead to hepatosplenic disease, and it may cause cardiopulmonary complications, including pulmonary hypertension.
Demosthenes G. Papamatheakis, Ana Olga H. Mocumbi, Nick H. Kim, Jess Mandel   +3 more
wiley   +1 more source

Multidrug Resistance: An Emerging Crisis

Interdisciplinary Perspectives on Infectious Diseases, Volume 2014, Issue 1, 2014., 2014
The resistance among various microbial species (infectious agents) to different antimicrobial drugs has emerged as a cause of public health threat all over the world at a terrifying rate. Due to the pacing advent of new resistance mechanisms and decrease in efficiency of treating common infectious diseases, it results in failure of microbial response ...
Jyoti Tanwar, Shrayanee Das, Zeeshan Fatima, Saif Hameed, Massimiliano Lanzafame   +4 more
wiley   +1 more source

Schistogram changes after administration of antischistosomal drugs in mice at the early phase of Schistosoma mansoni infection

Memorias do Instituto Oswaldo Cruz, 2013
Mice infected with Schistosoma mansoni were treated with oxamniquine, praziquantel, artesunate at the pre-patent phase, aiming at observing schistogram alterations.
Andrea Cassia Simoes Vimieiro, Neusa Araujo, Naftale Katz, John Robert Kusel, Paulo Marcos Zech Coelho   +4 more
doaj   +1 more source

Chromatographic Fingerprint Analysis and Effects of the Medicinal Plant Species Mitracarpus frigidus on Adult Schistosoma mansoni Worms

BioMed Research International, Volume 2014, Issue 1, 2014., 2014
The aims of this work were to evaluate the in vitro and in vivo schistosomicidal properties of the methanolic extract of the aerial parts of Mitracarpus frigidus (MFM) and to determine its HPLC profile. For the in vitro experiment, four pairs of adult worms, obtained from infected mice, were exposed to different concentrations of MFM (100 to 400 μg/mL)
Rodrigo Luiz Fabri, Danielle Maria de Oliveira Aragão, Jônatas Rodrigues Florêncio, Nícolas de Castro Campos Pinto, Ana Carolina Alves Mattos, Paulo Marcos Zech Coelho, Maria Christina Marques Nogueira Castañon, Eveline Gomes Vasconcelos, Priscila de Faria Pinto, Elita Scio, Gail B. Mahady   +10 more
wiley   +1 more source

Synthesis of 1,2,3‐Triazole‐Methyl‐Menadione Derivatives: Evaluation of Electrochemical and Antiparasitic Properties against two Blood‐Dwelling Parasites

ChemMedChem, Volume 20, Issue 6, March 15, 2025.
The present study describes the synthesis and thorough investigation of 1,2,3‐triazole‐methyl‐menadione derivatives with particular emphasis on their electrochemical and physicochemical properties and their antiparasitic activities against Plasmodium falciparum and Schistosoma mansoni. Although less effective against P.
Baptiste Dupouy, Tanja Karpstein, Cécile Häberli, Monica Cal, Matthias Rottmann, Pascal Mäser, Jennifer Keiser, Mourad Elhabiri, Elisabeth Davioud‐Charvet   +8 more
wiley   +1 more source

Cheminformatics Models for Inhibitors of Schistosoma mansoni Thioredoxin Glutathione Reductase

The Scientific World Journal, Volume 2014, Issue 1, 2014., 2014
Schistosomiasis is a neglected tropical disease caused by a parasite Schistosoma mansoni and affects over 200 million annually. There is an urgent need to discover novel therapeutic options to control the disease with the recent emergence of drug resistance.
Sonam Gaba, Salma Jamal, Open Source Drug Discovery Consortium, Vinod Scaria, Yudong Cai   +4 more
wiley   +1 more source

Treatment of schistosomiasis: gathering stones together

Memorias do Instituto Oswaldo Cruz, 1995
In this paper the treatment of schistosomiasis is examined under the following headings: cercarial dermatitis, Katayama fever, schistosomiasis in the immunosuppressed host and treatment of therapeutic failures.
J. R. Lambertucci
doaj   +1 more source

Ruthenium Catalysed Transfer Deuteration of Heteroaromatics in D2O

Asian Journal of Organic Chemistry, Volume 14, Issue 1, January 2025.
The partial reduction of heterocycles with selective deuterium incorporation using formic acid/sodium formate, D2O and a ruthenium catalyst was achieved. A biphasic medium (toluene/D2O) allowed excellent catalyst recycling. The ruthenium center allowed an inversion of polarity of D+ that was transformed into deuteride.
Carlos Gonzalo‐Navarro, Margarita Ruiz‐Castañeda, Jairo Fidalgo, Gustavo Espino, Félix A. Jalón, Blanca R. Manzano   +5 more
wiley   +1 more source

Antimicrobial Multidrug Resistance and Mechanisms of Action: An Overview

BioMed Research International, Volume 2025, Issue 1, 2025.
Antimicrobial multidrug resistance is the ability of microorganisms to withstand the effects of several antimicrobial agents, presenting a major challenge to modern healthcare systems worldwide. Although considerable research has been conducted, the molecular and evolutionary mechanisms underlying resistance are still not completely understood.
Abraham Belete Temesgen, Samuel Atalay Shiferaw, Baisakhi Banerjee   +2 more
wiley   +1 more source

From Incidentaloma to Suspicion of Malignancy: The Diverse Clinical Presentation of Gonadal Schistosomiasis mansoni

Case Reports in Infectious Diseases, Volume 2013, Issue 1, 2013., 2013
Schistosomiasis is the second most widespread parasitic disease in the world, second only to malaria. The usual places the Schistosoma mansoni can be found in are the rectal and sigmoidal venules, as well as other segments of the large intestine of men. It may also be present in other ectopic topographies.
Laiana do Carmo Almeida, Marbele Guimarães de Oliveira, Fábio Meira Castro Pereira, José de Bessa Júnior, J.-F. Faucher, M. Ghate, C. L. Gibert, P. Horrocks, A. C. Sena   +8 more
wiley   +1 more source