PLoS Neglected Tropical Diseases, 2020 Currently there is only one method of treatment for human schistosomiasis, the drug praziquantel. Strong selective pressure has caused a serious concern for a rise in resistance to praziquantel leading to the necessity for additional pharmaceuticals ...
Meghan A Guzman +11 more
doaj +1 more source
Ultrasonographic assessment of urinary tract lesions due to Schistosoma haematobium in Niger after four consecutive years of treatment with praziquantel [PDF]
, 1990 Une étude comparative sur l'étendue des lésions du tractus urinaire détectées par échographie a été entreprise dans 2 villages du Niger situés près de périmètres irrigués.
Develoux, M. +4 more
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Chemistry and the Worm: Caenorhabditis elegans as a Platform for Integrating Chemical and Biological Research [PDF]
, 2014 This Review discusses the potential usefulness of the worm Caenorhabditis elegans as a model organism for chemists interested in studying living systems. C. elegans, a 1 mm long roundworm, is a popular model organism in almost all areas of modern biology.
Hulme, S. Elizabeth +1 more
core +1 more source
Memorias do Instituto Oswaldo Cruz, 2007 Patients with acute schistosomiasis were studied before and after oxamniquine treatment. They had been exposed to cercariae 5 to 9 weeks before, and presented compatible clinical manifestations, eosinophilia, and high levels of total IgE.
Joelma R de Souza +8 more
doaj
Parasites & Vectors, 2018 Background Schistosomiasis is one of the most harmful parasitic diseases worldwide, praziquantel being the only drug in widespread use to treat it. We recently demonstrated that ferrocenyl, ruthenocenyl and benzyl derivatives of oxamniquine (Fc-OXA, Rc ...
Valentin Buchter +3 more
doaj +1 more source
The Development of a Direct Homologous Radioimmunoassay for Serum Cortisol [PDF]
, 1981 Peer ...
Giesemann, G. +4 more
core +2 more sources
QSAR-Driven Discovery of Novel Chemical Scaffolds Active against Schistosoma mansoni. [PDF]
, 2016 Schistosomiasis is a neglected tropical disease that affects millions of people worldwide. Thioredoxin glutathione reductase of Schistosoma mansoni (SmTGR) is a validated drug target that plays a crucial role in the redox homeostasis of the parasite.
Anne E. Carpenter +16 more
core +3 more sources
The immune-dependence of chemotherapy in experimental schistosomiasis
Memorias do Instituto Oswaldo Cruz, 1989 Experimental evidence indicates that immune effector mechanisms can enhance the activity of schistosomicidal drugs. Praziquantel, oxamniquine, hycanthone and antimony were less effective against Schistosoma mansoni infections in mice immunosuppressed by ...
M. J. Doenhoff
doaj +1 more source
Molluscicidal Activity of Legumes, Yellow Flame (Peltophorum Pterocarpum) and Raintree (Samanea Saman) on Freshwater Snails; Indoplanorbis Exustus (Pulmonata: Planorbidae) and Radix Quadrasi (Pulmonata: Lymnaeidae) [PDF]
, 2002 Acute toxicity by static bioassay of ground dried leaves (medium age) of leguminoses, yellow flame (Peltophorum pterocarpum) and rain tree (Samanea saman), in the form of ground powder solution, crude water and methanol extract was determined against ...
Bilal, Amal Ibrahim Khalifa
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Spektrofluorimetrijsko određivanje ciklopiroks olamina prevođenjem u ternarni kompleks s Tb(III) i EDTA [PDF]
, 2006 A highly sensitive and selective spectrofluorimetric method was developed for the determination of ciclopirox olamine in raw material and in dosage forms.
MANAL IBRAHIM EID +3 more
core +1 more source