Results 91 to 100 of about 572,637 (334)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Biological and Chemical Processes of Nitrate Reduction and Ferrous Oxidation Mediated by Shewanella oneidensis MR-1

open access: yesMicroorganisms
Iron, Earth’s most abundant redox-active metal, undergoes both abiotic and microbial redox reactions that regulate the formation, transformation, and dissolution of iron minerals.
Lingyu Hou   +6 more
doaj   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Study on transformation and removal of phosphorus species in the treatment of spent electroless nickel plating bath

open access: yesGongye shui chuli
Aiming at the difficult-to-treat high-concentration phosphorus in the spent electroless nickel plating baths, the transformation trends of phosphorus species in catalytic oxidation-reduction, H2O2 oxidation, calcium hypochlorite oxidation, and Fenton ...
TANG Yao   +4 more
doaj   +1 more source

Spectrophotometric Determination of Sulfacetamide in Pure Form and Pharmaceutical Formulations with Metol and potassium hexacyanoferrate (ΙΙΙ)

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences, 2012
A simple, sensitive and accurate spectrophotometric method of determination of Sulfacetamide (SAC) in pure form and pharmaceutical formulation. The method is based on the formation of (SAC) complex.
Ayad M.R. Raauf   +2 more
doaj   +1 more source

Ignition means for monopropellant Patent [PDF]

open access: yes, 1967
Catalyst bed ignition system for hydrazine ...
Evans, D. D., Lee, D. H.
core   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

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