Results 31 to 40 of about 4,265,820 (293)
Post-Electrophoretic Identification of Oxidized Proteins
The oxidative modification of proteins has been shown to play a major role in a number of human diseases. However, the ability to identify specific proteins that are most susceptible to oxidative modifications is difficult.
Conrad Craig +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Oxidation and Reduction of tert-Butylnitrosoacetylene
Tert-butylnitrosoacetylene [I] can be oxidized to the corresponding nitroacetylene [II] in spite of the low temperature rearrangement of [I] to the isomeric pivaloylcyanide [III].
Jean-Claude Motte, H.G. Viehe
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Flower development is a crucial and complex process in the reproductive stage of plants, which involves the interaction of multiple endogenous signals and environmental factors.
Fenqi Chen +8 more
doaj +1 more source
Redox transformations of iron at extremely low pH: fundamental and applied aspects
Many different species of acidophilic prokaryotes, widely distributed within the domains Bacteria and Archaea, can catalyze the dissimilatory oxidation of ferrous iron or reduction of ferric iron, or can do both.
D. Barrie eJohnson +2 more
doaj +1 more source
دراسة تعیین درجة حرارة حرق بعض الأوانی الفخاریة کأساس علمی لتشخیص مظاهرتلفها ( تل آثارالسمارة – عصرماقبل الأسرات - دراسة حالة ) [PDF]
Firing temperature degree of some pottery has been determined from Tel al-samara in Dakahlia through their examination and analysis by polarized microscope "PLM", scanning electron microscope SEM,X-ray diffraction XRD and thermal analysis TGA where the ...
Dr.Walid Kamel Ali Elghareb
doaj +1 more source
Considering the biological and ecological importance of Cu–thiol interactions and the discrepancies in previous research, this study focuses on Cu interactions with biologically and ecologically relevant thiols: glutathione (GSH), L-cysteine (L-cys), 3 ...
Dora Crmarić, Elvira Bura-Nakić
doaj +1 more source

