Results 21 to 30 of about 552,516 (264)

Changes in Sperm Glutathione and Glutathione Redox States Correlate to Poor Sperm Qualitative Measures

Reproductive Medicine
Background/Objectives: In the past 50 years, human reproductive capacity has steadily declined with elusive and idiopathic origins. Amongst theorized causes, oxidative stress has been proposed to directly contribute to male infertility.
Caroline G. Ploeger, Kate Hansen, Ammon Bayles, Adriana Burger, Jason Hansen, Timothy Jenkins   +5 more
doaj   +1 more source

Post-Electrophoretic Identification of Oxidized Proteins

Biological Procedures Online, 2000
The oxidative modification of proteins has been shown to play a major role in a number of human diseases. However, the ability to identify specific proteins that are most susceptible to oxidative modifications is difficult.
Conrad Craig, Talent John, Malakowsky Christina, Gracy Robert   +3 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Response of soil pH and electrical conductivity to climate, soil type, and water source, and their effect on rice grain yield in Sri Lankan lowlands

Circular Agricultural Systems
Soil pH and electrical conductivity (EC) are crucial determinants of rice productivity, as they influence nutrient solubility and osmotic regulation.
Sinthuja Sugathas, Charuka Chandrasekara, Anuththara Neththasinghe, Nipuna Thennakoon, Mojith Ariyarathna, Harsha Kadupitiya, Rohana Thilakasiri, Lalith Suriyagoda   +7 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Oxidation and Reduction of tert-Butylnitrosoacetylene

CHIMIA, 1975
Tert-butylnitrosoacetylene [I] can be oxidized to the corresponding nitroacetylene [II] in spite of the low temperature rearrangement of [I] to the isomeric pivaloylcyanide [III].
Jean-Claude Motte, H.G. Viehe
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

دراسة تعیین درجة حرارة حرق بعض الأوانی الفخاریة کأساس علمی لتشخیص مظاهرتلفها ( تل آثارالسمارة – عصرماقبل الأسرات - دراسة حالة ) [PDF]

Journal of General Union of Arab Archaeologists, 2016
Firing temperature degree of some pottery has been determined from Tel al-samara in Dakahlia through their examination and analysis by polarized microscope "PLM", scanning electron microscope SEM,X-ray diffraction XRD and thermal analysis TGA where the ...
Dr.Walid Kamel Ali Elghareb
doaj   +1 more source

Interaction between Cu and Thiols of Biological and Environmental Importance: Case Study Using Combined Spectrophotometric/Bathocuproine Sulfonate Disodium Salt Hydrate (BCS) Assay

Molecules, 2023
Considering the biological and ecological importance of Cu–thiol interactions and the discrepancies in previous research, this study focuses on Cu interactions with biologically and ecologically relevant thiols: glutathione (GSH), L-cysteine (L-cys), 3 ...
Dora Crmarić, Elvira Bura-Nakić
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source