Results 71 to 80 of about 7,572,002 (293)

Chemical party: spirits that are not so, drinks for no drinking and something to eat

open access: yesRevista Eureka sobre Enseñanza y Divulgación de las Ciencias, 2011
Se describen cuatro experimentos de reacciones químicas y propiedades de las soluciones presentados en forma lúdica, con la finalidad primero de atraer la atención para inmediatamente después provocar la reflexión acerca del fenómeno observado.
Corominas, Josep
doaj  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Spectrophotometric Determination of Aspirin in Pure Form and Pharmaceutical Formulations using Oxidation–reduction reaction

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences, 2010
A simple, sensitive and accurate spectrophotometric method of determination of aspirin in pure form and pharmaceutical formulation. The method is based on the formation of Prussian blue (PB) complex. The reaction between the acidic hydrolysis product of
Ayad M.R. Raauf   +2 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Determining the oxidative stability and quality of tiger nut (Cyperus esculentus) oil and its antioxidant activity during microwave heating

open access: yesRevista Española de Nutrición Humana y Dietética, 2018
Introduction: The emphasis on high-oleic vegetable oils is prominent in human communities all over the world. That being said, the high level of monounsaturated fatty acid (oleic acid) in tiger nut (Cyperus esculentus) oil shows that it is resistant to ...
Atoosa Sobhani   +3 more
doaj   +1 more source

Detailed Kinetic Mechanism for the Oxidation of Ammonia Including the Formation and Reduction of Nitrogen Oxides

open access: yesEnergy & Fuels, 2018
This work introduces a newly developed reaction mechanism for the oxidation of ammonia in freely propagating and burner-stabilized premixed flames as well as shock-tube, jet-stirred reactor, and plug-flow reactor experiments.
K. Shrestha   +3 more
semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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