Results 101 to 110 of about 1,412,233 (318)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Oxidation of an oil rich in docosahexaenoic acid compared to linoleic acid in lactating women [PDF]

open access: yes, 1999
Background: We studied the oxidation of an oil rich in docosahexaenoic acid (DHA; DHASCO(R)) in lactating mothers receiving a dietary DHA supplement or a placebo. The results were compared with the oxidation of linoleic acid.
Pohl, A.   +4 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Exploring Glyoxalase Strategies for Managing Sugar-Induced Chronic Diseases

open access: yesLife
The liver’s crucial role in methylglyoxal (MG) metabolism is frequently overlooked in the literature. We present a perspective that enhances the current understanding of the role of methylglyoxal (MG) and the glyoxalase cycle in the pathogenesis of ...
Alejandro Gugliucci
doaj   +1 more source

Paraoxonases (PON) 1, 2, and 3 Polymorphisms and PON-1 Activities in Patients with Sickle Cell Disease

open access: yesAntioxidants, 2019
(1) Background: Oxidative stress, chronic inflammation, vasoocclusion, and free iron are all features present in sickle cell disease. Paraoxonases (PON) are a family (PON-1, PON-2, PON-3) of antioxidant enzymes with anti-inflammatory action.
Cadiele Oliana Reichert   +8 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

CORRELATION AND PATH COEFFICIENT ANALYSIS FORYIELD AND SOME YIELD COMPONENTS OF WHEAT (Triticumaestivum L.)

open access: yes, 2017
The experiment was conducted to determine the relationship among yield and some yield components using correlation and path coefficient analysis. This study was performed under Mardin conditions the years of 2011-2012 and 2012-2013.
TOĞAY NECAT,TOĞAY YEŞİM,DOĞAN YUSUF   +1 more
core  

Development of quantitative techniques for the study of discharge events during plasma electrolytic oxidation processes

open access: yes, 2010
Plasma electrolytic oxidation, or PEO, is a surface modification process for the production of ceramic oxide coatings upon substrates of metals such as aluminium, magnesium and titanium.

core   +1 more source

Effects of Phenolic‐Rich Extra Virgin Olive Oil and Prebiotics on Sarcopenia in Older Adults: FOOP‐Sarc Project

open access: yesJournal of Cachexia, Sarcopenia and Muscle
Background Management of sarcopenia by nutritional and lifestyle interventions is a challenge. The aim is to assess the effectiveness of a phenolic‐rich extra virgin olive oil (EVOO), alone or combined with a prebiotic (PREB) (fructooligosaccharides and ...
Maria Besora‐Moreno   +12 more
doaj   +1 more source

Home - About - Disclaimer - Privacy