Results 51 to 60 of about 1,389,421 (297)
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Dissolved oxygen, due to atmospheric oxygen transfer through food, lowers the overall nutritional, chemical, and physical qualities of food during storage and marketing, causing food product less acceptable or unacceptable to consumers.
C. Pénicaud +3 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
On the kinetics of the oxidation of phloroglucinol
AbstractKinetic experiments indicate that the first step of the oxidation of phloroglucinol by Fe (CN)6 − − − is reversible. The equilibrium concerned, however, is not stable, since one of the species participating, i.e. the first oxidation product of phloroglucinol, is broken down irreversibly.
Stein, H.N., Tendeloo, H.J.C.
openaire +3 more sources
The kinetics of the dissolution of chalcopyrite in chloride media [PDF]
One of the most important outstanding problems with the hydrometallurgy of copper is the low temperature leaching of chalcopyrite. In this thesis, a fundamental study at low temperature was undertaken in order to establish a mechanism, which is ...
Velásquez Yévenes, Lilian
core
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Neural NetworkModeling of Oxidation Kinetics in Air of Steel-T21 Alloy Coated by Simultaneous Germanium-Doped Aluminizing-Silicon zing Process [PDF]
In this work a pack cementation of germanium-doped aluminum and silicon coatings on low alloy steel type-T21 has been applied. This gives significant improvement in the oxidation.
Abbas Khammas, Mohanned M. H.AL-Khafaji
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
The kinetics of the oxidation of ethylene [PDF]
Abstract The idea of chain reactions has long been familiar in connection with photochemical changes, but experimental evidence that thermal changes sometimes occur by a chain mechanism has only recently been forthcoming. In chain reactions the first transformation yields a product endowed with excess of energy which initiates a ...
Harold Warris Thompson +1 more
openaire +1 more source

