Results 91 to 100 of about 6,998,127 (315)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Fabrication and oxidation resistance of mullite/yttrium silicate multilayer coatings on C/SiC composites

Journal of Advanced Ceramics, 2017
A tri-layer coating of mullite/Y2Si2O7/(70wt%Y2Si2O7+30wt%Y2SiO5) was prepared on carbon fiber reinforced silicon carbide (C/SiC) composite substrate through dip-coating route for the sake of improving oxidation resistance of C/SiC composites.
Qingsong Ma, Lihui Cai
doaj   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

Preparation process of silicide coatings on molybdenum alloy surface by molten salt method

Fenmo yejin jishu
Using Na2B4O7, B4C, NaCl, KCl, NaF, Na2SiF6, and Si powders as the molten salt components, the Mo–Si–B composite coatings were prepared on the surface of molybdenum alloys by the molten salt method.
WANG Li, WANG Zhaoyu, HU Ping, HAN Jiayu, ZHAO Weiguo, GAO Lili, WANG Kuaishe   +6 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Water‐ and oxidation‐resistant MXenes for advanced electromagnetic interference shielding applications

InfoMat
Two‐dimensional transition metal carbides and nitrides (MXenes) show great promise for electromagnetic interference (EMI) shielding. However, their susceptibility to oxidation, particularly in humid environments or water, limits their industrial ...
Young Ho Jin, Ju‐Hyoung Han, Jaeeun Park, Mincheal Kim, Shi‐Hyun Seok, Yujin Chae, Yeoseon Sim, Sangjin Seo, Hyeonwoo Lee, Jaewon Wang, Jihoon Yang, Sora Jang, Juwon Han, Haeng Un Yeo, Sung Hyun Park, EunMi Choi, Taesung Kim, Soon‐Yong Kwon   +17 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Microstructure, mechanical properties and oxidation resistance of bulk W-B-Fe-Cr for fusion shielding

Nuclear Fusion
In this work, a bulk W-B-Fe-Cr shielding material with lower boron content (9.6 at.%) has been fabricated by hot isostatic pressing (HIP) for potential engineering applications in compact fusion reactors.
Z. Lv, C. Mao, W. Tang, W. Guo, J. Wang, J. Shi, S. Ma, H. Dai, J. Yang, W. Wang   +9 more
doaj   +1 more source