Results 111 to 120 of about 13,910,228 (354)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Superconductivity in the metallic-oxidized magnesium interface
, 2012 Metastable superconductivity at 39 - 54 K in the interfaces formed by metallic and oxidized magnesium (MgO) has been observed by ac magnetic susceptibility measurements.
Khasanov, S. S. +2 more
core +1 more source
, 2017 Nanosized Ir-black (3 nm) and Ir-oxide (5 nm) oxygen evolution electrocatalysts showing high performance in polymer electrolyte membrane (PEM) water electrolysis based on Aquivion ® short-side chain ionomer membrane are investigated to understand the ...
S. Siracusano +5 more
semanticscholar +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Proton Transfer Can Govern Regioselectivity Assisted by Iron Catalysis
iScience, 2020 Summary: Ortho-selective aromatic C-H functionalization is frequently used in organic synthesis and chemical/pharmaceutical industries. However, this reaction relies heavily on the use of directing groups suffering from limited substrate scope and extra ...
Yudong Li +6 more
doaj +1 more source
Plutonium oxidation states in seawater
Applied Radiation and Isotopes, 2001 Studies of the oxidation-state distribution of plutonium in the ocean illustrate the need to characterize seawater by means of the pH, the E(H), and quanititative complexation parameters. The parameters are combined in an easy-to-use equation that determines the fractions of the four oxidation states.
openaire +3 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Oxidation of GaN: An ab initio thermodynamic approach
, 2013 GaN is a wide-bandgap semiconductor used in high-efficiency LEDs and solar cells. The solid is produced industrially at high chemical purities by deposition from a vapour phase, and oxygen may be included at this stage.
Jackson, Adam J., Walsh, Aron
core +1 more source
Approaches for the quantitative analysis of oxidation state in cerium oxide nanomaterials
Nanotechnology, 2018 Cerium oxide nanomaterials (nanoceria, CNMs) are receiving increased attention from the research community due to their unique chemical properties, most prominent of which is their ability to alternate between the Ce3+ and Ce4+ oxidation states.
C. Sims +5 more
semanticscholar +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source