Results 71 to 80 of about 43,763 (313)

Solvent‐Free Thermal Defect Engineering in Molecular Frameworks With Volatile Linkers

Advanced Materials, EarlyView.
Thermal removal of neutral volatile linkers enables precise and solvent‐free generation of metal vacancies in MOFs. This strategy affords redox‐stable, coordinatively unsaturated FeII sites with tunable spin, ligand coordination, and catalytic behavior. The approach offers a general route to design defect‐functional materials through local coordination
Sonia Martínez‐Giménez, Alejandro Orellana‐Silla, Marta Galbiati, Efrén Navarro‐Moratalla, Luca Braglia, Sara Stolfi, José Antonio Real, Víctor Rubio‐Giménez, Sergio Tatay, Carlos Martí‐Gastaldo   +9 more
wiley   +1 more source

Unexpected Dual Function of Plant YUCCA Enzymes Links Chlorophyll Catabolism to Auxin Homeostasis

Angewandte Chemie, EarlyView.
YUCCA enzymes are well known to catalyze the main step of auxin biosynthesis in plants. Here, a hitherto undescribed dual function was discovered, revealing that some YUCCAs also act in chlorophyll degradation. In vitro feedback regulation furthermore suggests a link between chlorophyll degradation and hormone homeostasis and a physiological role of ...
Sina Rütschlin, Lei Zhang, Cornelia A. Karg, Michael Zwerger, Johanna M. Gostner, Simone Moser, Robin Teufel   +6 more
wiley   +2 more sources

Increasing cellular fitness and product yields in Pseudomonas putida through an engineered phosphoketolase shunt

Microbial Cell Factories, 2023
Background Pseudomonas putida has received increasing interest as a cell factory due to its remarkable features such as fast growth, a versatile and robust metabolism, an extensive genetic toolbox and its high tolerance to oxidative stress and toxic ...
Lyon Bruinsma, Maria Martin-Pascual, Kesi Kurnia, Marieken Tack, Simon Hendriks, Richard van Kranenburg, Vitor A. P. Martins dos Santos   +6 more
doaj   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

Electrochemical Degradation of Perfluoroalkyl Sulfonates via Sulfonate to Carboxylate Conversion

Angewandte Chemie, EarlyView.
We demonstrate a novel approach for the degradation of perfluoroalkyl sulfonic acids (PFSAs) involving a controlled, electromediated, sulfonate‐to‐carboxylate headgroup conversion. We apply this method to shorter chain PFSAs and provide key mechanistic insights that contribute to a broader understanding of the molecular pathways underlying pollutant ...
Stella A. Fors, Richard J. Monsky, Emily R. Mahoney, Christian A. Malapit, William R. Dichtel   +4 more
wiley   +2 more sources

An Alternative Mechanistic Paradigm for the Electrochemical C‐Terminal Decarboxylation of Peptides

ChemElectroChem
The C‐terminal decarboxylation of peptides provides an important opportunity to synthesize modern peptide pharmaceuticals that contain C‐terminal amides.
Adam J. Sowers, Kevin D. Moeller, Kim S. Halskov   +2 more
doaj   +1 more source

Genomic and Transcriptional Characteristics of Strain Rum-meliibacillus sp. TYF-LIM-RU47 with an Aptitude of Directly Producing Acetoin from Lignocellulose

Fermentation, 2022
Rummeliibacillus sp. TYF-LIM-RU47, isolated from the fermentation substrate of grain vinegar, could produce acetoin using a variety of carbon sources, including pentose, hexose and lignocellulose.
Guoyang Feng, Xiaojun Fan, Yanna Liang, Chen Li, Junde Xing, Yongji He   +5 more
doaj   +1 more source

Phosphatidylserine synthase 2 and phosphatidylserine decarboxylase are essential for aminophospholipid synthesis in Trypanosoma brucei [PDF]

, 2017
The work was supported by Swiss National Science Foundation grant 149353 to PB, Wellcome Trust grants 067441 and 093228 and European Community’s Seventh Framework Programme under grant agreement No.
Allemann, Arroyo-Olarte, Bannai, Baunaure, Bevers, Bligh, Bogdanov, Borkenhagen, Brun, Butler, Choi, Cullen, Desy, Dowhan, Elabbadi, Emoto, Fadok, Farine, Fevre, Finn, Gibellini, Gibellini, Gibellini, Gonzalez-Salgado, Gupta, Horvath, Ichimura, Kanfer, Kennedy, Kitamura, Kuge, Laemmli, Lee, Lilley, Matsumoto, Menon, Menon, Miller, Nerlich, Nikawa, Ohta, Poelje, Ramakrishnan, Redmond, Richmond, Rifkin, Rontein, Schneider, Schuiki, Schuiki, Schultz, Schumann Burkard, Serricchio, Serricchio, Signorell, Signorell, Signorell, Stone, Storey, Suzuki, Takai, Trotter, Trotter, Trotter, Vance, Vance, Vance, Vance, Vance, Vickerman, Voelker, Wirtz, Yamashita, Zhang   +73 more
core   +2 more sources

Systematic Metabolic Engineering and Model‐Guided Optimization for High‐Level Production of L‐Theanine From Xylose in Escherichia Coli

Advanced Science, EarlyView.
This study is pioneering in constructing the shortest known synthetic pathway for L‐theanine production from xylose within E coli. Through comprehensive metabolic engineering strategies, our engineered strain achieved the highest reported L‐theanine titer from xylose, with a titer of 95.42 g/L, and a yield of 0.55 g/g.
Haolin Han, Boyuan Xue, Guangqi Shan, Meng Meng, Shaojie Wang, Haijia Su   +5 more
wiley   +1 more source

SIRT3 and GCN5L regulation of NADP+- and NADPH-driven reactions of mitochondrial isocitrate dehydrogenase IDH2

Scientific Reports, 2020
Wild type mitochondrial isocitrate dehydrogenase (IDH2) was previously reported to produce oncometabolite 2-hydroxyglutarate (2HG). Besides, mitochondrial deacetylase SIRT3 has been shown to regulate the oxidative function of IDH2. However, regulation of
Katarína Smolková, Jitka Špačková, Klára Gotvaldová, Aleš Dvořák, Alena Křenková, Martin Hubálek, Blanka Holendová, Libor Vítek, Petr Ježek   +8 more
doaj   +1 more source