Results 101 to 110 of about 3,315,390 (285)

Hepatic Mitochondrial Defects in a Nonalcoholic Fatty Liver Disease Mouse Model Are Associated with Increased Degradation of Oxidative Phosphorylation Subunits*

Molecular & Cellular Proteomics, 2018
2H2O-metabolic labeling approach was used to assess hepatic mitochondrial proteome dynamics in a diet-induced mouse model of non-alcoholic fatty liver disease (NAFLD).
Kwangwon Lee, Andrew Haddad, A. Osme, Chunki Kim, Ahmad Borzou, S. Ilchenko, D. Allende, S. Dasarathy, A. McCullough, R. Sadygov, T. Kasumov   +10 more
semanticscholar   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Uncouplers of oxidative phosphorylation. [PDF]

Environmental Health Perspectives, 1990
Uncouplers of oxidative phosphorylation in mitochondria inhibit the coupling between the electron transport and phosphorylation reactions and thus inhibit ATP synthesis without affecting the respiratory chain and ATP synthase (H(+)-ATPase). Miscellaneous compounds are known to be uncouplers, but weakly acidic uncouplers are representative because they ...
openaire   +3 more sources

Inflammation Mediated By TNFα Disrupts the Autophagic Flux and Oxidative Phosphorylation of Megakaryocytes and Platelets through the Downregulation of STX17 [PDF]

, 2023
Guadalupe Rojas-Sánchez, Jorge Calzada-Martinez, Brandon McMahon, Orlando Esparza, Giovanny Hernandez, Dennis Le, Eric P. Wartchow, Tzu Phang, Travis Nemkov, Angelo D’Alessandro, Paola Maycotte, Andrew Thorburn, José A. López, Pavel Davizon‐Castillo   +13 more
openalex   +1 more source

Targeting Mitochondrial Oxidative Phosphorylation Abrogated Irinotecan Resistance in NSCLC

Scientific Reports, 2018
Anticancer drug resistance is a major challenge of cancer therapy. We found that irinotecan-resistant NSCLC cells showed increased mitochondrial oxidative phosphorylation compared to the drug sensitive NSCLC cells.
Soo-Mi Lee, Jae-Seon Lee, Jinho Seo, Seon-Hyeong Lee, J. Kang, Jaewhan Song, Soo‐Youl Kim   +6 more
semanticscholar   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Phosphorylation of Neuronal Nitric Oxide Synthase at Ser⁸⁴⁷ by CaM-KII in the Hippocampus of Rat Brain after Transient Forebrain Ischemia [PDF]

, 2002
Koji Osuka, Yasuo Watanabe, Nobuteru Usuda, Ayami Nakazawa, Kohji Fukunaga, Eishichi Miyamoto, Masakazu Takayasu, Masaaki Tokuda, Jun Yoshida   +8 more
openalex   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

The biochemistry of organotin compounds Trialkyltins and oxidative phosphorylation [PDF]

, 1958
W.N. Aldridge
openalex   +1 more source

Transcriptome analysis around the onset of strawberry fruit ripening uncovers an important role of oxidative phosphorylation in ripening

Scientific Reports, 2017
Although much progress has been made towards understanding the ripening of non-climacteric fruit using the strawberry as a model plant, the defined molecular mechanisms remain unclear.
Qing‐Hua Wang, Cheng-Ri Zhao, Miao Zhang, Yu-Zhong Li, Yuan-Yue Shen, Jiaxuan Guo   +5 more
semanticscholar   +1 more source