Results 291 to 300 of about 522,162 (364)

MTFR2‐Mediated Fission Drives Fatty Acid and Mitochondrial Co‐Transfer from Hepatic Stellate Cells to Tumor Cells Fueling Oncogenesis

Advanced Science, EarlyView.
In the tumor margin of hepatocellular carcinoma (HCC), activated hepatic stellate cells upregulate MTFR2, initiating inhibiting DRP1 degradation and mitochondrial fission. This enhances mitochondrial availability and facilitates FAs synthesis via ACC1. Additionally, fission promotes RAC1‐mediated cytoskeletal remodeling and Miro1‐mediated mitochondrial
La Zhang, Baoyong Zhou, Jun Yang, Cong Ren, Jing Luo, Zhenghang Li, Qiang Liu, Zuotian Huang, Zhongjun Wu, Ning Jiang   +9 more
wiley   +1 more source

Correction: Ceria nanoparticles ameliorate renal fibrosis by modulating the balance between oxidative phosphorylation and aerobic glycolysis. [PDF]

J Nanobiotechnology
Wang M, Zeng F, Ning F, Wang Y, Zhou S, He J, Li C, Wang C, Sun X, Zhang D, Xiao J, Hu P, Reilly S, Xin H, Xu X, Zhang X.   +15 more
europepmc   +1 more source

The Phosphorylation Reaction that Accompanies the Nonenzymic Oxidation of 2-Methyl-l,4-naphthohydroquinone Diphosphate

, 1964
Gordon E. Tomasi, R.Duncan Dallam
openalex   +1 more source

Gelsolin's Protective Role in MASH through F‐Actin Regulation and P53 Degradation

Advanced Science, EarlyView.
Gelsolin (GSN) maintains liver metabolic homeostasis by promoting MDM2‐mediated P53 degradation and inhibiting F‐actin/Yes‐associated protein (YAP) overactivation. Loss of GSN impairs P53 degradation, increases lipid deposition, and enhances YAP‐driven fibrosis and inflammation in metabolic‐associated steatohepatitis.
Yiwei Lu, Tong Ji, Zhichao Ye, Jianing Yan, Chao Wang, Jiachen Chen, Ziyang Jin, Yongji Zhu, Xiujun Cai, Yifan Wang   +9 more
wiley   +1 more source

Exploring Aerobic Energy Metabolism in Breast Cancer: A Mutational Profile of Glycolysis and Oxidative Phosphorylation. [PDF]

Int J Mol Sci
Oliveira RC, Cavalcante GC, Soares-Souza GB.   +2 more
europepmc   +1 more source

Partial Resolution of the Enzymes Catalyzing Oxidative Phosphorylation

, 1966
Yasuo Kagawa, Efraim Racker
openalex   +1 more source

Targeted STING Activation Using Modified Ultrasound‐Responsive Microbubbles Enhances Immune Checkpoint Blockade Against Melanoma

Advanced Science, EarlyView.
This study explores the use of ultrasound contrast agents loaded with Stimulator of Interferon Genes (STING) agonists as an approach to activate the body's immune system against cancer. Termed Microbubble‐assisted UltraSound‐guided Immunotherapy of Cancer (MUSIC), this strategy effectively inhibits tumor growth and improves survival in mouse models of ...
Sina Khorsandi, Kristin Huntoon, Yifan Wang, Adam Woodward, Abin Antony, Connor Endsley, Nazia Hafeez, Jared L. Edwards, Nicole McCuen, Prasanna G. Alluri, Betty Y.S. Kim, Wen Jiang, Jacques Lux   +12 more
wiley   +1 more source

PSENEN influences the progression of renal clear cell carcinoma by regulating the immune microenvironment and oxidative phosphorylation. [PDF]

PeerJ
Huang C, Chen K, Zhu S, Yang X, Hou J, Gu X.   +5 more
europepmc   +1 more source

Partial Resolution of the Enzymes Catalyzing Oxidative Phosphorylation

, 1967
Gottfried Schatz, Harvey S. Penefsky, Efraim Racker   +2 more
openalex   +1 more source

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

Advanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao, Rui‐Ling Wang, Ran‐Xin Liu, Meng‐Ru Zheng, Li Zhao, Bao‐Feng Li, Jia‐Le Li, De‐Shen Liu, Xiao‐Xia He, Qin‐Bao Peng, Kai Li, Tian‐Xiao Lin, Ying‐Ying Liu, Sheng‐Ping He, Jun Lu, Shao‐Yi Zheng, Xiu Liu, Fang‐Ze Huang   +17 more
wiley   +1 more source