Results 351 to 360 of about 6,984,973 (370)
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Oxidative Stress

EcoSal Plus, 2009
The ancestors of Escherichia coli and Salmonella ultimately evolved to thrive in air-saturated liquids, in which oxygen levels reach 210 μM at 37°C. However, in 1976 Brown and colleagues reported that some sensitivity persists: growth defects still become apparent when hyperoxia is imposed on
openaire   +2 more sources

Postprandial Oxidative Stress

Biological Chemistry, 2002
Consumption of a meal containing oxidized and oxidizable lipids gives rise to an increased plasma concentration of lipid hydroperoxides, detectable by a sensitive chemiluminescence procedure. This is associated with increased susceptibility of LDL to oxidation, apparently due a structural perturbation at the particle surface brought about by lipid ...
URSINI, FULVIO, A. SEVANIAN
openaire   +4 more sources

Metals, toxicity and oxidative stress.

Current Medicinal Chemistry, 2005
Metal-induced toxicity and carcinogenicity, with an emphasis on the generation and role of reactive oxygen and nitrogen species, is reviewed. Metal-mediated formation of free radicals causes various modifications to DNA bases, enhanced lipid peroxidation,
M. Valko, H. Morris, M. Cronin
semanticscholar   +1 more source

Homocysteine and oxidative stress

Amino Acids, 2003
Hyperhomocysteinemia is an independent risk factor for cardiovascular disease (ischemic disease, such as stroke and myocardial infarction, and arterial and venous thrombotic events) in the general population. We can assume that the association is causal, based on the example of homocystinuria, and on the evidence put forward by several basic science ...
PERNA, Alessandra   +2 more
openaire   +3 more sources

Oxidative stress, glutamate, and neurodegenerative disorders.

Science, 1993
There is an increasing amount of experimental evidence that oxidative stress is a causal, or at least an ancillary, factor in the neuropathology of several adult neurodegenerative disorders, as well as in stroke, trauma, and seizures.
J. Coyle, P. Puttfarcken
semanticscholar   +1 more source

Oxidant signals and oxidative stress

Current Opinion in Cell Biology, 2003
Although oxidants clearly possess the capacity to behave in a random and destructive fashion, growing evidence suggests that in many instances the production of reactive oxygen species is tightly regulated and their downstream targets exquisitely specific.
openaire   +3 more sources

Microcirculation and oxidative stress

Free Radical Research, 2007
The microcirculation is a complex and integrated system, transporting oxygen and nutrients to the cells. The key component of this system is the endothelium, contributing to the local balance between pro and anti-inflammatory mediators, hemostatic balance, as well as vascular permeability and cell proliferation.
CRIMI E, IGNARRO LJ, NAPOLI, Claudio
openaire   +4 more sources

Demystifying Oxidative Stress

2020
The hypothesis that reactive oxygen species (ROS) can be not just associated with but causally implicated in disease was first made in 1956, but so far, the oxidative stress theory of disease has not led to major therapeutic breakthrough, and the use of antioxidant is now confined to the field of complementary medicine. This chapter reviews the lack of
Ghezzi, Pietro, Mooradian, Arshag D
openaire   +3 more sources

Glucocorticoids and oxidative stress

Journal of Basic and Clinical Physiology and Pharmacology, 2007
Glucocorticoids (GC) are used widely for the treatment of patients with various disorders, including autoimmune diseases, allergies, and lymphoproliferative disorders. Glucocorticoid therapy is often limited by several adverse reactions associated with GC excess.
Bjelakovic, G   +9 more
openaire   +3 more sources

Oxidative stress, antioxidants and stress tolerance.

Trends in Plant Science, 2002
R. Mittler
semanticscholar   +1 more source

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