Results 111 to 120 of about 3,811,701 (363)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Research activities related to the role of forests and forestry in climate change mitigation in Austria. COST E21 Workshop. Contribution of forests and forestry to mitigate greenhouse effects. Joensuu (Finland). 28-30 Sep 2000 [PDF]
Biotechnologie, Agronomie, Société et Environnement, 2000 Forests and forestry play important roles in Austria with its close to 50/ forest cover. This paper provides details about the Austrian forest carbon inventory, discusses briefly the sources and sinks accounted under the land use, land use change and ...
Weiss P., Schlamadinger B.
doaj
Control of arsenic mobilization in paddy soils by manganese and iron oxides
, 2017 Reductive mobilization of arsenic (As) in paddy soils under flooded conditions is an important reason for the relatively high accumulation of As in rice, posing a risk to food safety and human health.
Peng Wang +9 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Toward the rational design of non-precious transition metal oxides for oxygen electrocatalysis
, 2015 In this Review, we discuss the state-of-the-art understanding of non-precious transition metal oxides that catalyze the oxygen reduction and evolution reactions.
W. Hong +5 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Formation of Multi-coatings on Nickel: Structure, Phase formation, Physical and Chemical Properties [PDF]
Журнал нано- та електронної фізики, 2015 Methods of aluminum-silicon and titanium-aluminum coatings of nickel in a mixture of metal powders, aluminum oxide Al2O3 and ammonium chloride NH4Cl were proposed.
V.G. Hignjak +5 more
doaj
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
, 2004 Deep convection causes thunderstorms with lightning. In this paper we summarise the nitrogen oxides results obtained from the recent measurements over Brazil within the experiment TROCCINOX and compare the results with the results from EULINOX and its ...
Gatzen, C. +5 more
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