Results 71 to 80 of about 63,046 (336)

Oxidized Phospholipids in Healthy and Diseased Lung Endothelium

Cells, 2020
Circulating and cell membrane phospholipids undergo oxidation caused by enzymatic and non-enzymatic mechanisms. As a result, a diverse group of bioactive oxidized phospholipids generated in these conditions have both beneficial and harmful effects on the
Pratap Karki, Konstantin G. Birukov
doaj   +1 more source

Influence of vitamin K antagonist treatment on activated partial thromboplastin time [PDF]

, 2015
A
Devreese, Katrien, MULLIEZ, SYLVIE, Van den Bogaert, Julie   +2 more
core   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Redox phospholipidomics analysis reveals specific oxidized phospholipids and regions in the diabetic mouse kidney

Redox Biology, 2022
While it is generally accepted that oxidative stress impacts the diabetic kidney and contributes to pathogenesis, there is a substantial lack of knowledge about the molecular entity and anatomic location of a variety of reactive species.
Allison McCrimmon, Sydney Corbin, Bindesh Shrestha, Gregory Roman, Suraj Dhungana, Krisztian Stadler   +5 more
doaj   +1 more source

Tuning ubiquinone position in biomimetic monolayer membranes [PDF]

, 2017
Artificial lipid bilayers have been extensively studied as models that mimic natural membranes (biomimetic membranes). Several attempts of biomimetic membranes inserting ubiquinone (UQ) have been performed to enlighten which the position of UQ in the ...
Guaus Guerrero, Ester, Hoyo Pérez, Javier, Torrent Burgués, Juan   +2 more
core   +2 more sources

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

A bioactive ginsenoside alleviates hepatocellular ferroptosis induced by oxidized phospholipid accumulation in nonalcoholic steatohepatitis

iMeta
Yibo Zong, Guo Long, Tiantian Gu, Pan Huang, Yong Tian, Wenwu Xu, Xiheng Hu, Dazun Shi, Lizhi Lu, Tao Zeng   +9 more
doaj   +2 more sources

ALOX15-launched PUFA-phospholipids peroxidation increases the susceptibility of ferroptosis in ischemia-induced myocardial damage

Signal Transduction and Targeted Therapy, 2022
Myocardial ischemia/reperfusion (I/R) injury is a classic type of cardiovascular disease characterized by injury to cardiomyocytes leading to various forms of cell death.
Xiao-Hui Ma, Jiang-Han-Zi Liu, Chun-Yu Liu, Wan-Yang Sun, Wen-Jun Duan, Guan Wang, Hiroshi Kurihara, Rong-Rong He, Yi-Fang Li, Yang Chen, Hongcai Shang   +10 more
doaj   +1 more source

Lipid peroxidation index of particulate matter: Novel metric for quantifying intrinsic oxidative potential and predicting toxic responses

Redox Biology, 2021
Using particulate matter (PM) mass as exposure metric does not reveal the intrinsic PM chemical characteristics or toxic potential, which is crucial for monitoring the sources of emission causing adverse health effects and developing risk mitigating ...
Sumit K. Dey, Kavya Sugur, Venkataramana G. Venkatareddy, Pradhi Rajeev, Tarun Gupta, Rajesh K. Thimmulappa   +5 more
doaj   +1 more source

Weight loss surgery in adolescents corrects high-density lipoprotein subspecies and their function. [PDF]

, 2017
Background/objectiveYouth with obesity have an altered high-density lipoprotein (HDL) subspecies profile characterized by depletion of large apoE-rich HDL particles and an enrichment of small HDL particles.
Davidson, WS, Elder, D, Heink, A, Hui, DY, Inge, TH, Kelesidis, T, Melchior, JT, Sexmith, H, Shah, AS   +8 more
core   +1 more source