Results 171 to 180 of about 505,050 (297)

Oxidized Phospholipids: Introduction and Biological Significance

, 2012
Zamani Mohammad, Swati Srivastav
openalex   +2 more sources

Antisense Oligonucleotide Directed to Human Apolipoprotein B-100 Reduces Lipoprotein(a) Levels and Oxidized Phospholipids on Human Apolipoprotein B-100 Particles in Lipoprotein(a) Transgenic Mice [PDF]

, 2008
Esther Merki, Mark J. Graham, Adam E. Mullick, Elizabeth R. Miller, Rosanne M. Crooke, Robert E. Pitas, Joseph L. Witztum, Sotirios Tsimikas   +7 more
openalex   +1 more source

Fever Inspiration: Precision Engineering for Safe and Systemic Immunotherapy

Advanced Science, EarlyView.
This review examines engineered fever therapy (EFT) as a novel cancer treatment, harnessing fever's immunomodulatory effects to enhance systemic immune responses. It explores molecular mechanisms, advances in nanotechnology‐driven thermal immunotherapy, and a bioengineered framework for precise, safe fever induction. The paper evaluates EFT's potential
Yang Li, Fulong Man, Jianwei Cheng, Li Chen, Yongyong Li, Haiqing Dong   +5 more
wiley   +1 more source

Structural Basis for the Recognition of Oxidized Phospholipids in Oxidized Low Density Lipoproteins by Class B Scavenger Receptors CD36 and SR-BI [PDF]

, 2009
Detao Gao, Mohammad Zahid Ashraf, Niladri Kar, De Lin, Lawrence M. Sayre, Eugene A. Podrez   +5 more
openalex   +1 more source

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

Advanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong, Yulong Li, Hui Liang, Zumei Wu, Shiqun Wang, Yichao Wang, Jieyu Xu, Yanning Lan, Maohua Cai, Guangzhao Pan, Haiyan Yang, Kai Miao, Zhe‐Sheng Chen, Fangfang Tao, Xuelei Ma, Jiang‐Jiang Qin   +15 more
wiley   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

Release and Capture of Bioactive Oxidized Phospholipids and Oxidized Cholesteryl Esters During Percutaneous Coronary and Peripheral Arterial Interventions in Humans

, 2014
Amir Ravandi, Gregor Leibundgut, Ming‐Yow Hung, Mitul Patel, Patrick M. Hutchins, Robert C. Murphy, Anand Prasad, Ehtisham Mahmud, Yury I. Miller, Edward A. Dennis, Joseph L. Witztum, Sotirios Tsimikas   +11 more
openalex   +1 more source

ZDHHC2‐Dependent Palmitoylation Dictates Ferroptosis and Castration Sensitivity in Prostate Cancer via Controlling ACSL4 Degradation and Lipid Peroxidation

Advanced Science, EarlyView.
Our study reveals a novel mechanism by which palmitoylation regulates ferroptosis and enzalutamide resistance in prostate cancer. Under enzalutamide resistance, the FOXA1/CXXC5/TET2 complex induces aberrant upregulation of ZDHHC2, which subsequently suppresses ferroptosis by mediating S‐palmitoylation of USP19 and degradation of ACSL4 protein in CRPC ...
Shuai Shao, Wei Li, Yulong Hong, Ruijiang Zeng, Liang Zhu, Lu Yi, Yuan Li, Yinhuai Wang, Haojie Huang, Xuewen Jiang, Xin Jin   +10 more
wiley   +1 more source

Effect of lipid-lowering medications on oxidized phospholipids in individuals with elevated LIPOPROTEIN(a). [PDF]

Atheroscler Plus
Koutsogianni AD, Barkas F, Tellis C, Tselepis A, Liamis G, Tsimikas S, Liberopoulos E.   +6 more
europepmc   +1 more source

Impact of a short-term low calorie diet alone or with interval exercise on quality of life and oxidized phospholipids in obese females. [PDF]

Physiol Behav, 2022
Gilbertson NM, Eichner NZM, Gaitán JM, Pirtle JM, Kirby JL, Upchurch CM, Leitinger N, Malin SK.   +7 more
europepmc   +1 more source