Results 101 to 110 of about 90,447 (247)

Identification of Candidate Blood Biomarkers of Recombinant Human Erythropoietin Administration Using Targeted Polar Metabolomics by HILIC‐MS/MS

open access: yesDrug Testing and Analysis, EarlyView.
Using targeted HILIC‐MS/MS metabolomics, inosine and hypoxanthine were identified as potential biomarkers of EPO administration. Their consistent and sensitive plasma responses highlight their promise for inclusion in the Athlete Biological Passport (ABP), warranting further investigation to enhance anti‐doping detection strategies. ABSTRACT Increasing
Olivier Salamin   +5 more
wiley   +1 more source

Supersulfide biology and translational medicine for disease control

open access: yesBritish Journal of Pharmacology, EarlyView., 2023
Abstract For decades, the major focus of redox biology has been oxygen, the most abundant element on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial respiratory chain, contributing to energy production in aerobic organisms. In addition, oxygen‐derived reactive oxygen species including hydrogen peroxide and nitrogen
Uladzimir Barayeu   +5 more
wiley   +1 more source

Transcriptomic and proteomic insights into feather keratin degradation by Fervidobacterium

open access: yesFrontiers in Microbiology
Keratin, one of the most recalcitrant and abundant proteins on Earth, constitutes a challenging and underutilized material for the poultry industry. Although it resists degradation by most commonly available enzymes, natural breakdown occurs through the ...
Rubén Javier-López   +3 more
doaj   +1 more source

Uric Acid‐Lowering and Anti‐Hyperuricemia Effects of Plant‐Based Nutraceuticals and Foods: A Review

open access: yesFood Chemistry International, EarlyView.
Increased UA production and/or decreased UA secretion cause hyperuricemia. Effects and mechanism of flavonoids in reducing UA are summarized. Terpenoids, saponins, alkaloids, vitamin C, polysaccharides, peptides are effective. Plant‐based foods with UA‐lowering ability are reviewed.
Linwei He, Wenjian Yang, Jianhui Liu
wiley   +1 more source

Curcuma comosa‐Derived Diarylheptanoid Ameliorates Ulcerative Colitis by Inhibiting JNK/NF‐κB and Activating AMPK/Nrf2 Pathways

open access: yesFood Frontiers, EarlyView.
In this study, we isolated and investigated the protective effect of 1,7‐diphenyl‐(6E)‐6‐hepten‐3‐ol (DPHP) against ulcerative colitis. Our results demonstrate that DPHP administration effectively alleviates colitis symptoms, inhibits inflammation, and strengthens antioxidant defense mechanisms. A combination of network pharmacology analysis, molecular
Van‐Long Truong   +2 more
wiley   +1 more source

Pyruvate-Ferredoxin Oxidoreductase

open access: hybrid, 1971
Kosaku Uyeda, Jesse C. Rabinowitz
openalex   +2 more sources

Exploring the Potential of Tsuruazuki Bean as a Functional Food to Curb Obesity Using Human Amniotic Epithelial Cells and 3T3‐L1 Preadipocytes

open access: yesFood Frontiers, EarlyView.
Obesity is a global health problem that requires research and regulatory attention. This research aims to investigate transcriptome‐wide changes induced by Vigna umbellata (Tsuruazuki) using a stem cell‐based tool and preadipocytes to explore its untapped potential as a functional food for anti‐obesity applications.
Elda Nurafnie Ibnu Rasid   +6 more
wiley   +1 more source

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