Lithospermic acid (LA) inactivates the p53 signaling pathway via directly targeting SIRT3, thereby alleviating oxidative stress and abnormal apoptosis in the progression of doxorubicin (Dox)‐induced cardiomyocytes. ABSTRACT Doxorubicin (Dox)‐induced cardiomyopathy (DIC) is characterized by significant myocardial damage that can progress to dilated ...
Yining Zhao +13 more
wiley +1 more source
Kinetic and Potentiometric Characteristics of Ferredoxin: NADP<sup>+</sup> Oxidoreductase from <i>Chlorobaculum tepidum</i>. [PDF]
Laibakojis D +3 more
europepmc +1 more source
NAD(P)H:Quinone Oxidoreductase Activity Is the Principal Determinant of β-Lapachone Cytotoxicity [PDF]
John J. Pink +5 more
openalex +1 more source
NQO1‐Responsive Prodrug for in Cellulo Release of Cytochalasin B as Cancer Cell‐Targeted Migrastatic
The design, synthesis, biochemical, and cell biological evaluation of the NQO1‐targeted prodrug BQTML‐CB is reported. BQTML‐CB selectively releases cytochalasin B upon activation by the quinone‐oxidoreductase NQO1 associated with invasiveness of cancer cells, representing a novel approach to improve cancer selectivity and reduce immunosuppressive ...
Mervic D. Kagho +10 more
wiley +1 more source
Retraction: NAD(P)H: Quinone oxidoreductase 1 deficiency conjoint with marginal vitamin C deficiency causes cigarette smoke induced myelodysplastic syndromes. [PDF]
PLOS One Editors.
europepmc +1 more source
Nrf2 induction potency of plant-derived compounds determined using an antioxidant response element luciferase reporter and conventional NAD(P)H-quinone acceptor oxidoreductase 1 activity assay [PDF]
Erina Tamaru +3 more
openalex +1 more source
Small changes in the activity of chloroplastic NADP+‐dependent ferredoxin oxidoreductase lead to impaired plant growth and restrict photosynthetic activity of transgenic tobacco plants [PDF]
Mohammad‐Reza Hajirezaei +6 more
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Mechanism elucidation of cell‐selective fluorescent probes
This perspective outlines five mechanistic strategies—Protein‐oriented, carbohydrate‐oriented, lipid‐oriented, gating‐oriented, and metabolism‐oriented live‐cell distinctions—for achieving cell‐selective fluorescence in live‐cell imaging. By classifying probes based on their interactions with proteins, carbohydrates, lipids, transporters, or metabolic ...
Sourav Sarkar, Young‐Tae Chang
wiley +1 more source
Beitrag zur Charakterisierung des Oxidoreductase-Inhibitors
H. Gallati
openalex +2 more sources
ERK-dependent proteasome degradation of Txnip regulates thioredoxin oxidoreductase activity [PDF]
Zachary T. Kelleher +4 more
openalex +1 more source

