Results 171 to 180 of about 90,447 (247)

Comparative Analysis of Heat Exposure‐Induced Molecular Changes in Two Turtle Species with Contrasting Thermal Adaptations

open access: yesIntegrative Zoology, EarlyView.
Protein processing in the endoplasmic reticulum is highlighted in response to heat stress in Platysternon megacephalum. Under heat stress, the up‐regulation of genes such as CHOP in protein processing in the endoplasmic reticulum pathway, along with the suppression of energy and lipid metabolism and the up‐regulation of JARID2 expression, leads to ...
Jian Hong   +7 more
wiley   +1 more source

Pyrroloquinoline Quinone Is an Effective Senomorphic Agent to Target the Pro‐Inflammatory Phenotype of Senescent Cells

open access: yesAging Cell, EarlyView.
As a natural senomorphic agent, PQQ targets the intracellular molecule. HSPA8 of senescent cells, resulting in significantly reduced expression of the SASP. PQQ holds prominent potential to delay chronological aging and ameliorate age‐related conditions by acting as an effective senomorphic agent.
Birong Jiang   +6 more
wiley   +1 more source

CD38‐Targeting Peptide Vaccine Ameliorates Aging‐Associated Phenotypes in Mice

open access: yesAging Cell, EarlyView.
Shangcheng Yu et al. revealed that CD38‐targeting peptide vaccine ameliorated aging‐associated physical and cognitive phenotypes in mice. CD38‐vaccine selectively depletes CD38+ myeloid cells, improves glucose tolerance, and enhances oxygen consumption.
Shangcheng Yu   +10 more
wiley   +1 more source

The RNF/NQR redox pumps: a versatile system for energy transduction in bacteria and archaea. [PDF]

open access: yesAppl Microbiol Biotechnol
Buckel W   +4 more
europepmc   +1 more source

MITOCHONDRIAL NADH - UBIQUINONE OXIDOREDUCTASE (Complex 1) DEFICIENCY IN AN INFANT WITH CONGENITAL LACTIC ACIDOSIS [PDF]

open access: bronze, 1984
Randall W. Moreadith   +9 more
openalex   +1 more source

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