Results 141 to 150 of about 62,951 (328)

Stereochemistry of the dTDP-glucose oxidoreductase reaction.

open access: hybrid, 1977
Carl E. Snipes   +4 more
openalex   +1 more source

P450 Oxidoreductase Deficiency: Loss of Activity Caused by Protein Instability From a Novel L374H Mutation [PDF]

open access: bronze, 2016
Shaheena Parween   +6 more
openalex   +1 more source

Phloretin Suppresses Preadipocyte Differentiation by Targeting PPARγ/Transferrin to Activate Ferroptosis Signaling Pathway

open access: yesFood Frontiers, EarlyView.
Phloretin alleviates HFD‐induced obesity and suppresses adipogenesis by activating the ferroptosis pathway, potentially via targeting PPARγ and transferrin. ABSTRACT Phloretin, a plant‐derived dihydrochalcone bioactive compound, potentially modulates preadipocyte differentiation, although this remains controversial and requires further clarification ...
Jie Li   +8 more
wiley   +1 more source

The gut microbiome promotes the growth performance of black soldier fly larvae by detoxifying uric acid

open access: yesiMetaOmics, EarlyView.
This study demonstrates the detrimental effects of exogenous uric acid (UA) on the growth of black soldier fly (BSF) larvae, highlighting the role of gut microbiota in UA degradation. We isolated UA‐degrading bacterial strains associated with BSF, including Enterococcus faecalis AHAU24.
Xiaowen Ji   +12 more
wiley   +1 more source

Effects of catechins, resveratrol, silymarin components and some of their conjugates on xanthine oxidase‐catalyzed xanthine and 6‐mercaptopurine oxidation

open access: yesJournal of the Science of Food and Agriculture, Volume 105, Issue 5, Page 2765-2776, 30 March 2025.
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik   +6 more
wiley   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

open access: yesPediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu   +4 more
wiley   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella   +6 more
wiley   +1 more source

University proceedings. Volga region. Natural sciences

open access: yesИзвестия высших учебных заведений. Поволжский регион: Естественные науки
Background. For scientifically substantiated and effective application of new biocidal compounds as means of protecting industrial materials from biodamage, ecophysiological studies are necessary to assess their effect on destructor microorganisms.
A.Yu. Shishkin   +4 more
doaj   +1 more source

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