Results 21 to 30 of about 90,159 (370)
Frontiers in Oncology, 2014 Endoplasmic reticulum (ER) chaperones and oxidoreductases are abundant enzymes that mediate the production of fully folded secretory and transmembrane proteins. Resisting the Golgi and plasma membrane-directed bulk flow, ER chaperones and oxidoreductases
Thomas eSimmen, Tomas eGutierrez
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Enzymatic Bioprospecting of Fungi Isolated from a Tropical Rainforest in Mexico
Journal of Fungi, 2021 The humid tropical environment provides an ideal place for developing a high diversity of plants; this is why it is an interesting site for the enzymatic bioprospecting of fungi that are responsible for the recycling of organic matter in an efficient and
Karla Peraza-Jiménez +4 more
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Redox Out of the Box: Catalytic Versatility Across NAD(P)H-Dependent Oxidoreductases.
Angewandte Chemie, 2023 The asymmetric reduction of double bonds using NAD(P)H-dependent oxidoreductases has proven to be an efficient tool for the synthesis of important chiral molecules in research and on industrial scale. These enzymes are commercially available in screening
Sebastian Roth +3 more
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Targeting of the intracellular redox balance by metal complexes towards anticancer therapy
Frontiers in Chemistry, 2022 The development of cancers is often linked to the alteration of essential redox processes, and therefore, oxidoreductases involved in such mechanisms can be considered as attractive molecular targets for the development of new therapeutic strategies.
María Isabel Murillo +2 more
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Exploring Oxidoreductases from Extremophiles for Biosynthesis in a Non-Aqueous System
International Journal of Molecular Sciences, 2023 Organic solvent tolerant oxidoreductases are significant for both scientific research and biomanufacturing. However, it is really challenging to obtain oxidoreductases due to the shortages of natural resources and the difficulty to obtained it via ...
Shizhen Wang, Hangbin Lei, Zhehui Ji
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Cancers, 2022 Simple Summary Hypoxia-activated prodrugs (HAPs), selectively reduced by specific oxidoreductases under hypoxic conditions, form cytotoxic agents damaging the local cancer cells. On the basis of the reported clinical data concerning several HAPs, one can
Ewelina Janczy-Cempa +3 more
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Clinical evaluation of oxidative stress in patients with diabetes mellitus type II: Impact of acute exercise [PDF]
Vojnosanitetski Pregled, 2009 Background/Aim. Exercise is a well recognized model of oxidative stress and, also, an important tool in diabetes management. The aim of our study was to evaluate oxidative stress in patients with diabetes mellitus type 2 and to determine influence of ...
Kostić Nada +6 more
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Inspired by Nature—Functional Analogues of Molybdenum and Tungsten-Dependent Oxidoreductases
Molecules, 2022 Throughout the previous ten years many scientists took inspiration from natural molybdenum and tungsten-dependent oxidoreductases to build functional active site analogues.
Sebastian Pätsch +4 more
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Biomolecules, 2022 The worldwide access to pharmaceuticals and their continuous release into the environment have raised a serious global concern. Pharmaceuticals remain active even at low concentrations, therefore their occurrence in waterbodies may lead to successive ...
Helena Sá +3 more
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The oxidoreductases POR and CYB5R1 catalyze lipid peroxidation to execute ferroptosis
Molecular & Cellular Oncology, 2021 Our recent study showed that two oxidoreductases – NADPH-cytochrome P450 reductase (POR) and NADH-cytochrome b5 reductase (CYB5R1) – transfer electrons to oxygen to generate hydrogen peroxide (H2O2).
Youwei Ai, Bo Yan, Xiaodong Wang
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