Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages [PDF]
, 2008 This study provides the proof of principle that probing the host and the microbe transcriptomes simultaneously is a valuable means to accessing unique information on host pathogen interactions.
A Kolb-Maurer +86 more
core +10 more sources
Characterization of three pyranose dehydrogenase isoforms from the litter-decomposing basidiomycete Leucoagaricus meleagris (syn. Agaricus meleagris) [PDF]
, 2016 Nicht verfügbarMultigenicity is commonly found in fungal enzyme systems, with the purpose of functional compensation upon deficiency of one of its members or leading to enzyme isoforms with new functionalities through gene diversification. Three genes of
Graf, Michael M. H. +7 more
core +4 more sources
A study of hierarchical and flat classification of proteins [PDF]
, 2008 Automatic classification of proteins using machine learning is an important problem that has received significant attention in the literature. One feature of this problem is that expert-defined hierarchies of protein classes exist and can potentially be ...
Buchwald, Fabian +3 more
core +2 more sources
Differential expression and co-expression gene networks reveal candidate biomarkers of boar taint in non-castrated pigs [PDF]
, 2017 Boar taint (BT) is an offensive odour or taste observed in pork from a proportion of non-castrated male pigs. Surgical castration is effective in avoiding BT, but animal welfare issues have created an incentive for alternatives such as genomic selection.
Do, Duy N. +4 more
core +3 more sources
Dramatic down-regulation of oxidoreductases in human hepatocellular carcinoma hepG2 cells: proteomics and gene ontology unveiling new frontiers in cancer enzymology [PDF]
, 2008 Background Oxidoreductases are enzymes that catalyze many redox reactions in normal and neoplastic cells. Their actions include catalysis of the transformation of free, neutral oxygen gas into oxygen free radicals, superoxide, hydroperoxide, singlet ...
Ngoka, Lambert CM
core +4 more sources
Designing organometallic compounds for catalysis and therapy [PDF]
, 2012 Bioorganometallic chemistry is a rapidly developing area of research. In recent years organometallic compounds have provided a rich platform for the design of effective catalysts, e.g. for olefin metathesis and transfer hydrogenation.
Abraha Habtemariam +188 more
core +1 more source
Associated bacteria affect sexual reproduction by altering gene expression and metabolic processes in a biofilm inhabiting diatom [PDF]
, 2019 Diatoms are unicellular algae with a fundamental role in global biogeochemical cycles as major primary producers at the base of aquatic food webs. In recent years, chemical communication between diatoms and associated bacteria has emerged as a key factor
Bilcke, Gust +9 more
core +2 more sources
Mining the Flavoproteome of Brucella ovis, the Brucellosis causing agent in Ovis aries [PDF]
, 2022 Flavoproteins are a diverse class of proteins that are mostly enzymes and contain as cofactors flavin mononucleotide (FMN) and/or flavin adenine dinucleotide (FAD), which enable them to participate in a wide range of physiological reactions.
Martínez Júlvez, M. +3 more
core +1 more source
Thioredoxin reductase as a target enzyme for electrophilic anticancer drugs [PDF]
, 2011 Induced production of reactive oxygen species (ROS) is a common attribute of most cancer cells. One strategy for cancer cells to maneuver the increased and potentially toxic levels of ROS is to induce the expression of cellular antioxidants and ...
Eriksson, Sofi
core +1 more source
Insights from a Multi-Omics Integration (MOI) Study in Oil Palm (Elaeis gineensis Jacq.) Response to Abiotic Stresses: Part Two - Drought. [PDF]
, 2022 Drought and salinity are two of the most severe abiotic stresses affecting agriculture worldwide and bear some similarities regarding the responses of plants to them.
ABDELNUR, P. V. +9 more
core +1 more source