Repetitive and Non-Repetitive DNA Sequences and a Speculation on the Origins of Evolutionary Novelty [PDF]
Recent experimental information on DNA sequence repetition is reviewed, and the significance of both repetitive and non-repetitive sequence considered.
Britten, Roy J., Davidson, Eric H.
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Thioredoxin reductase as a target enzyme for electrophilic anticancer drugs [PDF]
Induced production of reactive oxygen species (ROS) is a common attribute of most cancer cells. One strategy for cancer cells to maneuver the increased and potentially toxic levels of ROS is to induce the expression of cellular antioxidants and ...
Eriksson, Sofi
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Associated bacteria affect sexual reproduction by altering gene expression and metabolic processes in a biofilm inhabiting diatom [PDF]
Diatoms are unicellular algae with a fundamental role in global biogeochemical cycles as major primary producers at the base of aquatic food webs. In recent years, chemical communication between diatoms and associated bacteria has emerged as a key factor
Bilcke, Gust +9 more
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Sugar metabolism, redox balance and oxidative stress response in the respiratory yeast [PDF]
A lot of studies have been carried out on Saccharomyces cerevisiae, an yeast with a predominant fermentative metabolism under aerobic conditions, which allows exploring the complex response induced by oxidative stress. S.
M Isabel González-Siso +3 more
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Mining the Flavoproteome of Brucella ovis, the Brucellosis causing agent in Ovis aries [PDF]
Flavoproteins are a diverse class of proteins that are mostly enzymes and contain as cofactors flavin mononucleotide (FMN) and/or flavin adenine dinucleotide (FAD), which enable them to participate in a wide range of physiological reactions.
Martínez Júlvez, M. +3 more
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Deep Eutectic Solvents: The Organic Reaction Medium of the Century [PDF]
This microreview summarizes the use of deep eutectic solvents (DESs) and related melts in organic synthesis. Solvents of this type combine the great advantages of other proposed environmentally benign alternative solvents, such as low toxicity, high ...
Abbott +192 more
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The genome of the intracellular bacterium of the coastal bivalve, Solemya velum: a blueprint for thriving in and out of symbiosis [PDF]
Background: Symbioses between chemoautotrophic bacteria and marine invertebrates are rare examples of living systems that are virtually independent of photosynthetic primary production.
Cavanaugh, Colleen M +13 more
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The pyruvate and α-ketoglutarate dehydrogenase complexes of Pseudomonas aeruginosa catalyze pyocyanin and phenazine-1-carboxylic acid reduction via the subunit dihydrolipoamide dehydrogenase [PDF]
Phenazines are a class of redox-active molecules produced by diverse bacteria and archaea. Many of the biological functions of phenazines, such as mediating signaling, iron acquisition, and redox homeostasis, derive from their redox activity.
Glasser, Nathaniel R. +3 more
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Atherothrombosis and Oxidative Stress: Mechanisms and Management in Elderly [PDF]
Significance: The incidence of cardiovascular events (CVEs) increases with age, representing the main cause of death in an elderly population. Aging is associated with overproduction of reactive oxygen species (ROS), which may affect clotting and ...
Carnevale, Roberto +4 more
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Paradoxical roles of antioxidant enzymes:Basic mechanisms and health implications [PDF]
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated from aerobic metabolism, as a result of accidental electron leakage as well as regulated enzymatic processes.
Amit R. Reddi +38 more
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