Results 51 to 60 of about 5,693 (184)
Journal of Ginseng Research, 2023 Background: The genus Panax in the Araliaceae family has been used as traditional medicinal plants worldwide and is known to biosynthesize ginsenosides and phytosterols.
Hyunjin Koo +11 more
doaj +1 more source
Frontiers in Plant Science, 2023 Metabolic gene clusters (MGCs) are groups of genes involved in a common biosynthetic pathway. They are frequently formed in dynamic chromosomal regions, which may lead to intraspecies variation and cause phenotypic diversity.
Malgorzata Marszalek-Zenczak +9 more
doaj +1 more source
Anti-Trypanosoma cruzi action of a new benzofuran derivative based on amiodarone structure [PDF]
, 2018 Chagas disease is a neglected tropical affection caused by the protozoan parasite Trypanosoma cruzi. There is no current effective treatment since the only two available drugs have a limited efficacy and produce side effects.
Benaim, Gustavo +4 more
core +1 more source
Enzyme-catalyzed cationic epoxide rearrangements in quinolone alkaloid biosynthesis. [PDF]
, 2017 Epoxides are highly useful synthons and biosynthons for the construction of complex natural products during total synthesis and biosynthesis, respectively.
Garcia-Borràs, Marc +8 more
core
Antifungal activity of bis-azasqualenes, inhibitors of oxidosqualene cyclase.
Mycoses, 2009 The antifungal activity and in vitro toxicity toward animal cells of two inhibitors of oxidosqualene cyclase, squalene bis-diethylamine (SBD) and squalene bis-diethylmethylammonium iodide (SBDI) were studied. Minimum inhibitory concentration (MIC) against dermatophytes and other fungi involved in cutaneous and systemic infections (12 isolates from ...
VOYRON, Samuele +7 more
openaire +3 more sources
Plant Biotechnology Journal, EarlyView.ABSTRACT Microalgae are increasingly recognised as powerful platforms for the sustainable production of lipids and terpenoids, with expanding applications in the food, fuel and biomanufacturing industries. In this updated review, we consolidate and critically assess the most recent advances in synthetic biology and metabolic engineering of key ...
Ty Shitanaka +6 more
wiley +1 more source
The genome of the Tiger Milk mushroom, Lignosus rhinocerotis, provides insights into the genetic basis of its medicinal properties [PDF]
, 2014 BACKGROUND: The sclerotium of Lignosus rhinocerotis (Cooke) Ryvarden or Tiger milk mushroom (Polyporales, Basidiomycota) is a valuable folk medicine for indigenous peoples in Southeast Asia. Despite the increasing interest in this ethnobotanical mushroom,
Chon-Seng Tan +6 more
core +1 more source
A Single Oxidosqualene Cyclase Produces the Seco-Triterpenoid α-Onocerin [PDF]
Plant Physiology, 2017 8,14-seco-Triterpenoids are characterized by their unusual open C-ring. Their distribution in nature is rare and scattered in taxonomically unrelated plants. The 8,14-seco-triterpenoid α-onocerin is only known from the evolutionarily distant clubmoss genus Lycopodium and the leguminous genus Ononis, which makes the biosynthesis of this seco ...
Aldo Almeida +8 more
openaire +6 more sources
Angewandte Chemie, Volume 137, Issue 4, January 21, 2025.A structure‐agnostic bioactivity‐driven combinatorial biosynthesis workflow is presented that introduces bioactivity assessment as a selection‐driving force to guide iterative combinatorial biosynthesis rounds towards enzyme combinations with increasing bioactivity.
Yong Zhao +7 more
wiley +2 more sources
Paleoproterozic Icehouses and the Evolution of Oxygen Mediating Enzymes: The Case for a Late Origin of Photosystem -- II [PDF]
, 2008 Two major geological problems regarding the origin of oxygenic photosynthesis are: (1) identifying a source of oxygen predating biological oxygen production and capable of driving the evolution of oxygen tolerance, and (2) determining when oxygenic ...
Kirschvink, Joseph L., Kopp, Robert E.
core