Results 281 to 290 of about 60,467 (293)

Cell Biological Consequences of OXPHOS Disorders

2007
During the past century mitochondria have been recognized to play a central role in many cellular functions. Apart from producing cellular energy in the form of ATP (adenosine 5′-triphosphate) this organelle harbors essential parts of the urea cycle and is crucial for the breakdown of fatty acids, heat generation and the biosynthesis of heme ...
Werner J. H. Koopman, Henk-Jan Visch, Sjoerd Verkaart, Peter H. G. M. Willems   +3 more
openaire   +1 more source

Mitochondrial pharma-Q-genomics: Targeting the OXPHOS cytochrome b

Drug Discovery Today, 2011
Genetic variation in human cytochrome b generates structurally different coenzyme Q binding pockets, affects the coupling efficiency of the oxidative phosphorylation system and susceptibility to different medical conditions. As modification of coupling efficiency has already been shown to have therapeutic interest, these structural differences might be
Gómez-Durán A, Pacheu-Grau D, López-Pérez MJ, Montoya J, Ruíz-Pesini E   +4 more
openaire   +3 more sources

Astrocytic OxPhos: more than just energy production

Nature Metabolism, 2023
Luis F. Rubio-Atonal, Maria S. Ioannou
openaire   +2 more sources

Molecular Biology of the OXPHOS System

2007
The mitochondrion contains a circular DNA genome (mtDNA) that serves as the basis for its own genetic system. This system is semiautonomous because the coding capacity of mtDNA is Umited to 13 subunits of the respiratory chain apparatus and the rRNAs and tRNAs necessary for their translation. The inheritance of mtDNA differs from that of nuclear DNA in
openaire   +1 more source

In vivo and in organello assessment of OXPHOS activities

Methods, 2002
Mitochondrial OXPHOS defects are responsible for a large group of human diseases and have been associated with degenerative disorders and aging. The accurate in vivo and in organello biochemical assessment of the OXPHOS system is necessary for the diagnosis and investigation of such conditions.
openaire   +2 more sources

OXPHOS Disorders

2013
Suzanne Macari, Ruth Eren, Louise Spear-Swerling, John T. Danial, Lawrence David Scahill, Fred R. Volkmar, Kevin A. Pelphrey, Winifred Schultz-Krohn, Brett Yamane, L. Lee Carlisle, Bryan King, Vicki Madaus Knapp, David McAdam, Fred R. Volkmar, Dorrey Sproatt, Anahita Navab, Rhea Paul, Katherine Tyson, Deborah Fein, Allison Bean, Casey Zampella, Loisa Bennetto, Allison Bean, Allison Bean, Devon Hartford, Stephen R. Hooper, Lauren Turner Brown, Fred R. Volkmar, Jennifer McCullagh, Patricia Howlin, Philippa Moss, David McAdam, Vicki Madaus Knapp   +32 more
openaire   +1 more source

Lactylation constrains OXPHOS under hypoxia

Cell Research
Haowen Ren, Di Zhang
openaire   +2 more sources

Uncovering the OXPHOS complexes' interdependence mechanism

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2022
Kristýna Čunátová, Marek Vrbacký, Guillermo Puertas-Frias, Jan Eliáš, Josef Houštěk, Alena Pecinová, Petr Pecina, Tomáš Mráček   +7 more
openaire   +1 more source

Oxidative Phosphorylation (OXPHOS)

2012
openaire   +1 more source

Organization and mechanisms of OXPHOS biogenesis

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2022
openaire   +1 more source