Results 31 to 40 of about 1,387,037 (263)

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

Isotope investigation of shallow aquifers in Chott Djerid, Southwestern Tunisia

open access: yesAcque Sotterranee
Groundwater is a crucial resource for various purposes, especially in the arid land of Southern Tunisia. The assessment of its properties needs a deeper understanding of the main mineralization processes.
Zohra Kraiem   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Variation of tap-water isotope ratios and municipal water sources across Kyiv city, Ukraine

open access: yesDiscover Water, 2022
Stable isotopes of water allow researchers to examine water pathways and better understand spatial and temporal variability in mixtures of municipal water sources.
Elizabeth Avery   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

The pronounced seasonality of global groundwater recharge

open access: yesWater Resources Research, 2014
Groundwater recharged by meteoric water supports human life by providing two billion people with drinking water and by supplying 40% of cropland irrigation.
Scott Jasechko   +7 more
doaj   +1 more source

INTERPRETATION OF OXYGEN –18 ISOTOPE IN SULPHATE FROM DEEP GROUNDWATER IN JAKARTA AREA

open access: yesIndonesian Journal of Chemistry, 2010
It has been done a determination of d 18O (SO42-) and d 18O (H2O) value from Jakarta deep groundwater with depth 40-140 m. The aim of this research is to know some procesess influencing the composition of oxygen isotope in groundwater sulphate.
E. Ristin Pujiindiyati   +2 more
doaj   +1 more source

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